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Gene Information
Gene symbol: PGR
Gene name: progesterone receptor
HGNC ID: 8910
Synonyms: PR, NR3C3
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
17440722
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As a source of antigens, we prepared protein lysates from four breast cancer cell lines (AU565, BT474, MCF-7 and MDA-MB-231) which in vitro exhibit different features of invasion, estrogen receptor/progesterone receptor status and HER2/neu expression thereby potentially representing mild to aggressive forms of clinical disease.
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2 |
22057675
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The ubiquitin-like protein, ISG15, is a novel tumor-associated antigen for cancer immunotherapy.
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3 |
22057675
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ISG15 is a small ubiquitin-like protein regulated by type-I interferon and classically associated with viral defense.
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4 |
22057675
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Elevated ISG15 expression in breast cancer is especially well documented and is independent of HER2, progesterone receptor, and estrogen receptor status.
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5 |
22057675
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We demonstrate that vaccination against ISG15 results in significant CD8-mediated reductions in both primary and metastatic mammary tumor burden.
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6 |
23634195
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Triple-negative breast cancer (TNBC), as defined by the absence of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 expression, is a challenging disease with the poorest prognosis of all breast cancer subtypes.
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