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Gene Information

Gene symbol: PGRMC1

Gene name: progesterone receptor membrane component 1

HGNC ID: 16090

Synonyms: HPR6.6

Related Genes

#	Gene Symbol	Number of hits
1	CD79A	1 hits
2	CTBS	1 hits
3	ERVWE1	1 hits

Related Sentences

#	PMID	Sentence
1	18708113	Induction of HIV-1 MPR(649-684)-specific IgA and IgG antibodies in caprine colostrum using a peptide-based vaccine.
2	25155369	The transmembrane (TM) domain of gp41 not only anchors the envelope glycoprotein complex in the viral membrane but also dynamically affects the interactions of the MPR with the membrane.
3	25295172	CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functions.
4	25295172	The first variant contained a flexible GPGP linker between CTB and MPR, and yielded crystals that diffracted to a resolution of 2.3 Å, but only the CTB region was detected in the electron-density map.
5	25295172	A third construct containing a polyalanine linker between CTB and MPR proved to stabilize the pentameric form of the protein during purification.
6	25295172	CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functions.
7	25295172	The first variant contained a flexible GPGP linker between CTB and MPR, and yielded crystals that diffracted to a resolution of 2.3 Å, but only the CTB region was detected in the electron-density map.
8	25295172	A third construct containing a polyalanine linker between CTB and MPR proved to stabilize the pentameric form of the protein during purification.
9	25295172	CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functions.
10	25295172	The first variant contained a flexible GPGP linker between CTB and MPR, and yielded crystals that diffracted to a resolution of 2.3 Å, but only the CTB region was detected in the electron-density map.
11	25295172	A third construct containing a polyalanine linker between CTB and MPR proved to stabilize the pentameric form of the protein during purification.
12	26295457	The membrane proximal region (MPR, residues 649-683) and transmembrane domain (TMD, residues 684-705) of the gp41 subunit of HIV-1's envelope protein are highly conserved and are important in viral mucosal transmission, virus attachment and membrane fusion with target cells.