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Gene Information
Gene symbol: PHGDH
Gene name: phosphoglycerate dehydrogenase
HGNC ID: 8923
Synonyms: SERA, PGDH, PDG
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ARHGEF7 | 1 hits |
| 2 | CASP8 | 1 hits |
| 3 | CCDC91 | 1 hits |
| 4 | CDKN2C | 1 hits |
| 5 | CSF2 | 1 hits |
| 6 | IFNG | 1 hits |
| 7 | IL12A | 1 hits |
| 8 | ING1 | 1 hits |
| 9 | RPIA | 1 hits |
| 10 | RPS27A | 1 hits |
| 11 | TP73 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2052035 | The first (SERA 1), corresponding to amino acids 24-285 of the natural SERA precursor, was expressed by the ubiquitin fusion method. |
| 2 | 2052035 | The second, larger protein (SERA N), encompassing amino acids 24-506, was expressed at only low levels using this system, but could be isolated in high yields when fused to human gamma-interferon (gamma-IFN). |
| 3 | 2052035 | The first (SERA 1), corresponding to amino acids 24-285 of the natural SERA precursor, was expressed by the ubiquitin fusion method. |
| 4 | 2052035 | The second, larger protein (SERA N), encompassing amino acids 24-506, was expressed at only low levels using this system, but could be isolated in high yields when fused to human gamma-interferon (gamma-IFN). |
| 5 | 11269323 | Furthermore, these levels were increased by the coinoculation of cytokine (IFN-gamma, IL-4, GM-CSF, or IL-12) expression plasmid. |
| 6 | 11269323 | In respect to the SERA-specific Ig subclasses, coinoculation of IFN-gamma, GM-CSF, or IL-12 expression plasmid increased the levels of SERA-specific IgG2a, and these were much higher than that in mice immunized with SERA expression plasmid alone. |
| 7 | 11897123 | The Plasmodium falciparum serine repeat antigen (SERA), a malaria vaccine candidate, is processed into several fragments (P73, P47, P56, P50, and P18) at the late schizont stage prior to schizont rupture in the erythrocytic cycle of the parasite. |
| 8 | 11897123 | The activity responsible for the primary processing step of SERA to P47 and P73 was inhibited by serine protease inhibitor DFP. |
| 9 | 11897123 | The Plasmodium falciparum serine repeat antigen (SERA), a malaria vaccine candidate, is processed into several fragments (P73, P47, P56, P50, and P18) at the late schizont stage prior to schizont rupture in the erythrocytic cycle of the parasite. |
| 10 | 11897123 | The activity responsible for the primary processing step of SERA to P47 and P73 was inhibited by serine protease inhibitor DFP. |
| 11 | 12542086 | These genes encode D-3-phosphoglycerate dehydrogenase (serA), ribose 5-phosphate isomerase (rpiA), a specific inhibitor of chromosomal initiation of replication (iciA), a hypothetical protein (yggE), a protein involved in responses to osmotic stress (yggB), fructose 1,6-bisphosphate aldolase (fda), and phosphoglycerate kinase (pgk). |
| 12 | 23582016 | SERA proteins have a unique putative papain-like cysteine protease motif that has either serine or cysteine in its active site. |