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Gene Information

Gene symbol: PICALM

Gene name: phosphatidylinositol binding clathrin assembly protein

HGNC ID: 15514

Synonyms: CALM, CLTH

Related Genes

# Gene Symbol Number of hits
1 ABCA7 1 hits
2 SORL1 1 hits

Related Sentences

# PMID Sentence
1 25748120 Thus missense, splice site or duplication mutants in the presenilin 1 (PS1), presenilin 2 (PS2) or the amyloid precursor protein (APP) genes, which alter the levels or shift the balance of Aβ produced, are associated with rare, highly penetrant autosomal dominant forms of Familial Alzheimer's Disease (FAD).
2 25748120 Similarly, the more prevalent late-onset forms of AD are associated with both coding and non-coding variants in genes such as SORL1, PICALM and ABCA7 that affect the production and clearance of Aβ.