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Gene Information
Gene symbol: PKM2
Gene name: pyruvate kinase, muscle
HGNC ID: 9021
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADPGK | 1 hits |
| 2 | GCK | 1 hits |
| 3 | GPD1 | 1 hits |
| 4 | GPD2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24556090 | Activated T cells show induced expression of, among other things, Glucose Transporter 1 and several glycolytic enzymes, including ADP-Dependent Glucokinase and the low affinity isoform Pyruvate Kinase-M2 (which promote glycolytic flux), as well Glutamine Transporters and Glycerol-3-phosphate Dehydrogenase 2 which make available glutamate and glycerol-3-phosphate as mitochondrial energy sources. |
| 2 | 24556090 | Unlike effector CD4(+) and CD8(+) T cells, Tregs and memory T cells oxidize fatty acids for fuel. |
| 3 | 24556090 | Upon activation, T cells express the insulin and leptin receptors on their surface and become sensitive to insulin signaling and nutrient availability and show changes in differentiation. |