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Gene Information

Gene symbol: POMGNT1

Gene name: protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase

HGNC ID: 19139

Synonyms: FLJ20277, MGAT1.2, LGMD2O

Related Genes

# Gene Symbol Number of hits
1 GBGT1 1 hits
2 MGAT2 1 hits
3 RENBP 1 hits
4 SAA4 1 hits

Related Sentences

# PMID Sentence
1 16800641 These results show that the biosynthesis of Vi antigen is initiated by the TviB-catalyzed oxidation of UDP-GlcNAc to UDP-GalNAc, followed by the TviC-catalyzed epimerization at C-4 to form UDP-GalNAcA, which serves as the building block for the formation of Vi polymer.
2 24795453 Mice carrying a myeloid-specific knockout of the Mgat2 gene encoding UDP-GlcNAc:α-6-d-mannoside β-1,2-N-acetylglucosaminyltransferase II enzyme exhibit deficiencies in IgG responses to both protein and polysaccharide conjugate vaccines.
3 24849599 Thereby the open reading frames csaA, -B, and -C are thought to encode the UDP-N-acetyl-D-glucosamine-2-epimerase, poly-ManNAc-1-phosphate-transferase, and O-acetyltransferase, respectively.
4 24849599 If recombinant CsaA and CsaB were combined in one reaction tube, priming CPSA-oligosaccharides were efficiently elongated with UDP-GlcNAc as the donor substrate, confirming that CsaA is the functional UDP-N-acetyl-D-glucosamine-2-epimerase and CsaB the functional poly-ManNAc-1-phosphate-transferase.