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Gene Information
Gene symbol: PROCR
Gene name: protein C receptor, endothelial
HGNC ID: 9452
Synonyms: EPCR, CCD41, CD201
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APC | 1 hits |
| 2 | F2R | 1 hits |
| 3 | MARK2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19404546 | Here, we present novel insights into the participation of DV in the downregulation of the thrombomodulin-thrombin-protein C complex formation at the endothelial surface, with a reduction in activated protein C (APC). |
| 2 | 19404546 | APC is the most important vasoprotective protein because it downregulates thrombin generation (by the inactivation of procoagulant factors Va and VIIIa) and has anti-inflammatory, antiapoptotic, and barrier protection properties. |
| 3 | 19404546 | These biological functions of APC are associated with the endothelial protein C receptor (EPCR) and protease-activated receptor 1 (PAR-1) signalling pathways, which link the coagulation-inflammation responses. |