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Gene Information
Gene symbol: PTGER4
Gene name: prostaglandin E receptor 4 (subtype EP4)
HGNC ID: 9596
Synonyms: EP4
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | PTGER2 | 1 hits |
| 2 | PTGER3 | 1 hits |
| 3 | SPAG11B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12149218 | Surprisingly, we found that for all maturation stimuli tested, the addition of prostaglandin E2 (PGE2) was required for effective migration of MoDCs toward the lymph node-derived chemokines CCL19 (EBI1 ligand chemokine/macrophage inflammatory protein--3beta) and CCL21 (secondary lymphoid tissue chemokine [SLC]/6Ckine). |
| 2 | 12149218 | Costimulation with PGE2 enhanced the expression of the CCL19/CCL21 receptor CCR7 on the cell surface of MoDCs when they were matured with soluble CD40 ligand or proinflammatory cytokines, but did not affect CCR7 expression of polyI:C-stimulated MoDCs. |
| 3 | 12149218 | The effects of PGE2 on MoDCs were mediated through increased cyclic adenosine monophosphate by 2 of the known PGE2 receptors, EP2 and EP4, which are expressed and down-regulated after PGE2 binding in these cells. |
| 4 | 25692534 | LipL32 epitopes, EP2, EP3, EP4, and EP6 are found to be promising B-cell epitopes for vaccine development. |