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Gene Information

Gene symbol: PTK2

Gene name: PTK2 protein tyrosine kinase 2

HGNC ID: 9611

Synonyms: FAK, FADK, FAK1, PPP1R71

Related Genes

#	Gene Symbol	Number of hits
1	CCL5	1 hits
2	MAPK3	1 hits
3	SRC	1 hits

Related Sentences

#	PMID	Sentence
1	14506272	We demonstrate here that US28 signals through the non-receptor protein-tyrosine kinases Src and focal adhesion kinase (FAK) and that this activity is necessary for US28-mediated SMC migration.
2	14506272	This association occurs earlier than the formation of the FAK.Src kinase complex, suggesting that US28 activates Src before FAK.
3	14506272	US28 binding to RANTES also promotes the formation of a Grb2.FAK complex, which is sensitive to treatment with the Src inhibitor PP2, further highlighting the critical role of Src in US28 activation of FAK.
4	14506272	These findings demonstrate that activation of FAK and Src plays a critical role in US28-mediated signaling and SMC migration.
5	14506272	We demonstrate here that US28 signals through the non-receptor protein-tyrosine kinases Src and focal adhesion kinase (FAK) and that this activity is necessary for US28-mediated SMC migration.
6	14506272	This association occurs earlier than the formation of the FAK.Src kinase complex, suggesting that US28 activates Src before FAK.
7	14506272	US28 binding to RANTES also promotes the formation of a Grb2.FAK complex, which is sensitive to treatment with the Src inhibitor PP2, further highlighting the critical role of Src in US28 activation of FAK.
8	14506272	These findings demonstrate that activation of FAK and Src plays a critical role in US28-mediated signaling and SMC migration.
9	14506272	We demonstrate here that US28 signals through the non-receptor protein-tyrosine kinases Src and focal adhesion kinase (FAK) and that this activity is necessary for US28-mediated SMC migration.
10	14506272	This association occurs earlier than the formation of the FAK.Src kinase complex, suggesting that US28 activates Src before FAK.
11	14506272	US28 binding to RANTES also promotes the formation of a Grb2.FAK complex, which is sensitive to treatment with the Src inhibitor PP2, further highlighting the critical role of Src in US28 activation of FAK.
12	14506272	These findings demonstrate that activation of FAK and Src plays a critical role in US28-mediated signaling and SMC migration.
13	14506272	We demonstrate here that US28 signals through the non-receptor protein-tyrosine kinases Src and focal adhesion kinase (FAK) and that this activity is necessary for US28-mediated SMC migration.
14	14506272	This association occurs earlier than the formation of the FAK.Src kinase complex, suggesting that US28 activates Src before FAK.
15	14506272	US28 binding to RANTES also promotes the formation of a Grb2.FAK complex, which is sensitive to treatment with the Src inhibitor PP2, further highlighting the critical role of Src in US28 activation of FAK.
16	14506272	These findings demonstrate that activation of FAK and Src plays a critical role in US28-mediated signaling and SMC migration.
17	19229316	While US28 binding of both RANTES and Fractalkine activate FAK and ERK-1/2, RANTES signals through Galpha12 and Fractalkine through Galphaq.