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Gene Information
Gene symbol: RAB14
Gene name: RAB14, member RAS oncogene family
HGNC ID: 16524
Synonyms: FBP, RAB-14
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD8A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22523066 | CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease. |
| 2 | 22523066 | Both CD4(+) and CD8(+) T cells mediate vaccine-induced protection from experimental aspergillosis, but the molecular mechanisms leading to the generation of protective immunity and whether these mechanisms are dysregulated in individuals with CGD have not been determined. |
| 3 | 22523066 | Aspergillus conidia activated CD8(+) T cells upon sorting to the Rab14(+) endosomal compartment required for alternative MHC class I presentation. |
| 4 | 22523066 | Our study thus indicates that distinct intracellular pathways are exploited for the priming of CD4(+) and CD8(+) T cells to A. fumigatus and suggests that CD4(+) T cell vaccination may be able to overcome defective antifungal CD8(+) T cell memory in individuals with CGD. |