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Gene Information
Gene symbol: RAB8A
Gene name: RAB8A, member RAS oncogene family
HGNC ID: 7007
Synonyms: RAB8
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD80 | 1 hits |
| 2 | CD81 | 1 hits |
| 3 | CTAG1B | 1 hits |
| 4 | HLA-DRB1 | 1 hits |
| 5 | MLANA | 1 hits |
| 6 | TYR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12604804 | Furthermore, cell-associated and secreted E2-661 protein bound to the major extracellular loop (MEL) of CD81 in a concentration-dependent manner and both were highly reactive with sera from HCV-infected patients. |
| 2 | 14996751 | We demonstrated previously that the vaccine cells present tumor peptides via the endogenous antigen presentation pathway to activate CD4(+) and CD8(+) T cells. |
| 3 | 14996751 | To obtain MHC class II(+)CD80(+)Ii(-) human tumor cells, we developed retroviruses encoding HLA-DR and CD80. |
| 4 | 14996751 | SUM159PT mammary carcinoma and Mel 202 ocular melanoma cells transduced with the retroviruses DRB1/CD80 express high levels of DRB0101 and CD80 on the cell surface in the absence of Ii. |
| 5 | 14996751 | Irradiated SUM159PT/DR1/CD80 vaccines stimulate proliferation of non-HLA-DRB0101 peripheral blood mononuclear cells and present an exogenous DR1-restricted tetanus toxoid (TT) peptide, indicating that the transduced DRB0101 is functional. |
| 6 | 14996751 | SUM159PT/DR1/CD80 vaccines were further transduced with a retrovirus encoding the TT fragment C gene, as a model tumor antigen. |
| 7 | 14996751 | Depletion and antibody blocking experiments confirm that MHC class II-restricted, endogenously synthesized epitopes are presented to CD4(+) T cells. |
| 8 | 14996751 | Therefore, the MHC class II vaccines are efficient antigen-presenting cells that activate tumor-specific MHC class II-restricted, CD4(+) T lymphocytes, and they are a novel and potential immunotherapeutic for metastatic cancers. |
| 9 | 15384929 | Eighteen of these patients also received vaccination with influenza (Flu), Melan-A (Mel), tyrosinase (Tyr), and NY-ESO-1 peptides. |
| 10 | 15384929 | FL induced increases in immature CD11c+ and CD123+ peripheral blood (PB) DCs. |