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Gene Information
Gene symbol: RLTPR
Gene name: RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
HGNC ID: 27089
Synonyms: LRRC16C, CARMIL2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL4 | 1 hits |
| 2 | LGMN | 1 hits |
| 3 | PRKAR1A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16943295 | Fiber binds with high affinity to the cell surface coxsackievirus-and-adenovirus receptor (CAR), and penton base facilitates viral internalization by binding alphav integrins through an RGD motif. |
| 2 | 24810641 | Then, as tolerance to self-antigens can be broken by the activation of CD4 T-cell help, we tried to enhance the immunogenicity of legumain by the insertion of a foreign helper epitope, namely the p30 epitope from the tetanus toxin. |
| 3 | 24810641 | The addition of the p30 helper epitope induced the specific production of IFN-γ by T cells, but did not significantly increase legumain-specific immunity activated after mutagenesis in the RGD motif which might be caused by simultaneous activation of a Th2 response demonstrated by the production of IL-4. |
| 4 | 24810641 | However, the beneficial effect of the helper epitope on legumain-specific response was proved after the depletion of regulatory T cells by antibody against CD25 that preferentially stimulated Th1 immunity. |