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Gene Information
Gene symbol: ROCK1
Gene name: Rho-associated, coiled-coil containing protein kinase 1
HGNC ID: 10251
Synonyms: p160ROCK
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | APAF1 | 1 hits |
| 3 | CASP7 | 1 hits |
| 4 | CASP9 | 1 hits |
| 5 | DFFA | 1 hits |
| 6 | DFFB | 1 hits |
| 7 | PDLIM5 | 1 hits |
| 8 | RHOD | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17018635 | After screening 3 x 10(6) clones from 3 different cDNA libraries, 15 tumor antigens were identified, including cytokeratin 2-8, glutamyl-prolyl-tRNA synthetase, complement C3, galectin 8, and serine/threonine-rich protein kinase 1. |
| 2 | 17018635 | Multiple proteins involved in the Rho/Rho-associated, coiled coil-containing protein kinase (Rock) signal transduction pathway were found to be immunogenic, including Rock1, Rho/Rac guanine nucleotide exchange factor 2, and schistosoma mansoni adult worm antigen preparation 70. |
| 3 | 22249285 | We report that hepatitis B vaccine exposure resulted in significant upregulation of the key genes encoding caspase 7, caspase 9, Inhibitor caspase-activated DNase (ICAD), Rho-associated coiled-coil containing protein kinase 1 (ROCK-1), and Apoptotic protease activating factor 1 (Apaf-1). |
| 4 | 22249285 | Upregulation of cleaved caspase 3,7 were detected by western blot in addition to Apaf-1 and caspase 9 expressions argues that cell death takes place via the intrinsic apoptotic pathway in which release of cytochrome c from the mitochondria triggers the assembly of a caspase activation complex. |
| 5 | 24696479 | ROCK1 and LIM kinase modulate retrovirus particle release and cell-cell transmission events. |