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Gene Information
Gene symbol: RSAD2
Gene name: radical S-adenosyl methionine domain containing 2
HGNC ID: 30908
Synonyms: cig5, viperin, vig1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EIF2AK2 | 1 hits |
| 2 | IFIT5 | 1 hits |
| 3 | IFITM3 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | IRAK1 | 1 hits |
| 6 | IRF7 | 1 hits |
| 7 | ISG15 | 1 hits |
| 8 | PLSCR1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17428947 | Five days after infection, these animals produced a potent, innate antiviral immune response by inducing the transcription of signature genes from the interferon (IFN) pathway with demonstrated antiviral activity, such as myxoprotein, 2',5'-oligoadenylate synthetase, phospholipid scramblase 1, and viperin. |
| 2 | 17428947 | Unexpectedly, no up-regulation of IFN-alpha, -beta, or -gamma genes was detected. |
| 3 | 17428947 | Transcription of the genes of interleukin-10 (IL-10), IL-8, IL-6, and tumor necrosis factor alpha was neither up-regulated nor down-regulated. |
| 4 | 22243898 | Transcriptional analysis further revealed that the expression levels of type I IFN system genes including interferon regulation factor-7 (IRF-7) gene, myxovirus resistance (Mx) gene and virus inhibitory protein (Viperin) gene were strongly up-regulated after injection with pcDNA-G, whereas the level of transcription of immunoglobulin M (IgM) gene did not show a statistically significant change. |
| 5 | 24996122 | All three IFN plasmids induced expression of antiviral genes (Mx, Viperin, ISG15 and IFIT5) at the muscle injection site while the control plasmid had little effect. |
| 6 | 24996122 | Injection of IFNc plasmid was found to induce expression of antiviral genes and receptors for virus RNA (RIG-I, TLR3 and TLR7) in head kidney from 1 to at least 8 weeks. |
| 7 | 25038286 | The expression levels of type I IFN system genes including IRF-7, IRAK1, Mx and Viperin were up-regulated at 6 h, and reached a peak at 48 h. |
| 8 | 26099219 | Transcriptional analysis of non-specific and specific immune related genes revealed that the expression levels of IRF-7, IRAK1, Mx, Viperin, and IgM were strongly up-regulated in the vaccinated groups post-immunization. |
| 9 | 26238721 | Moreover, the expression of several candidate genes, such as type I interferons, PKR, OAS, viperin and IFITM3 was quantified at 3, 8 and 18h post-treatment with TLR ligands. |