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Gene Information

Gene symbol: RUNX2

Gene name: runt-related transcription factor 2

HGNC ID: 10472

Synonyms: AML3, PEBP2A1, PEBP2aA1

Related Genes

# Gene Symbol Number of hits
1 MYC 1 hits
2 ODC1 1 hits
3 RUNX3 1 hits

Related Sentences

# PMID Sentence
1 19412607 It has been known that ornithine decarboxylase (ODC) induced by the binding of c-Myc to odc gene is closely linked to cell death.
2 19412607 ODC expression was increased by bacteria or LPS and repressed by inhibitors against mitogen-activated protein kinases (MAPKs) in Toll-like receptor 4 (TLR4) signaling pathway.
3 19412607 The cell death induced by bacteria was significantly decreased after treatment of CCD or c-Myc inhibitor, indicating that cell death by S. typhimurium infection is related to c-Myc, but not ODC.
4 26001080 A recent study has shown that transcriptional regulators of core binding factor (Cbf) β2 and promotor-1-transcribed Runt-related transcription factor 1 (P1-Runx1) are required for the differentiation of CD3-CD4+CD45+ lymphoid tissue inducer (LTi) cells, which initiate and trigger the developmental program of PPs, but the involvement of this pathway in NALT and TALT development remains to be elucidated.
5 26001080 However, in contrast to PPs, NALT and TALT developed normally in the absence of P1-Runx1 or other Runx family members such as Runx2 and Runx3.