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Gene Information
Gene symbol: RUNX3
Gene name: runt-related transcription factor 3
HGNC ID: 10473
Synonyms: AML2, PEBP2A3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCOR | 1 hits |
| 2 | EOMES | 1 hits |
| 3 | ID2 | 1 hits |
| 4 | RUNX2 | 1 hits |
| 5 | TCF7 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25768938 | Transcription factor expression patterns in SIV-specific CD8+ T cells in SIVΔnef-vaccinated animals were distinct from those observed in purified CD8+ T cell subsets obtained from naïve animals, and were intermediate to expression profiles of purified central memory and effector memory T cells. |
| 2 | 25768938 | Expression of transcription factors associated with effector differentiation, such as ID2 and RUNX3, were decreased over time, while expression of transcription factors associated with quiescence or memory differentiation, such as TCF7, BCOR and EOMES, increased. |
| 3 | 25768938 | CD8+ T cells specific for a more conserved epitope expressed higher levels of TBX21 and BATF, and appeared more effector-like than cells specific for an escaped epitope, consistent with continued activation by replicating vaccine virus. |
| 4 | 26001080 | A recent study has shown that transcriptional regulators of core binding factor (Cbf) β2 and promotor-1-transcribed Runt-related transcription factor 1 (P1-Runx1) are required for the differentiation of CD3-CD4+CD45+ lymphoid tissue inducer (LTi) cells, which initiate and trigger the developmental program of PPs, but the involvement of this pathway in NALT and TALT development remains to be elucidated. |
| 5 | 26001080 | However, in contrast to PPs, NALT and TALT developed normally in the absence of P1-Runx1 or other Runx family members such as Runx2 and Runx3. |