Ignet

Gene Information

Gene symbol: SAA

Gene name: serum amyloid A1 cluster

HGNC ID: 10512

Related Genes

#	Gene Symbol	Number of hits
1	APLP2	1 hits
2	APOA1	1 hits
3	APOA4	1 hits
4	APOE	1 hits
5	CFB	1 hits
6	CRP	1 hits
7	FANCA	1 hits
8	GPHA2	1 hits
9	HP	1 hits
10	IL1B	1 hits
11	IL6	1 hits
12	ITGAM	1 hits
13	LPAL2	1 hits
14	SERPINA3	1 hits
15	SH3BP5	1 hits
16	TNF	1 hits
17	TTR	1 hits

Related Sentences

#	PMID	Sentence
1	7369609	The SAA and FAA antigens were chemically modified by conjugation with dodecanoic acid (SAADA and FAADA).
2	9548303	Typhoid vaccination increased levels of SAA, haptoglobin alpha1, haptoglobin alpha2, haptoglobin beta and alpha1-anti-chymotrypsin but decreased transthyretin and apolipoprotein E.
3	9548303	In RA patients, serum amyloid A (SAA), haptoglobin alpha2, haptoglobin beta, alpha1-antichymotrypsin and C3 proactivator levels were elevated while apolipoprotein A-I, apolipoprotein A-IV, transthyretin, Gc-globulin, alpha2-HS glycoprotein, alpha2-macroglobulin and alpha1-B glycoprotein levels were decreased, compared to normals.
4	9548303	Compared to piroxicam, tenidap lowered levels of alpha1-antiprotease and SAA but raised the levels of transthyretin, Gc-globulin, alpha2-HS-glycoprotein and alpha2-macroglobulin in RA patients.
5	9548303	Typhoid vaccination increased levels of SAA, haptoglobin alpha1, haptoglobin alpha2, haptoglobin beta and alpha1-anti-chymotrypsin but decreased transthyretin and apolipoprotein E.
6	9548303	In RA patients, serum amyloid A (SAA), haptoglobin alpha2, haptoglobin beta, alpha1-antichymotrypsin and C3 proactivator levels were elevated while apolipoprotein A-I, apolipoprotein A-IV, transthyretin, Gc-globulin, alpha2-HS glycoprotein, alpha2-macroglobulin and alpha1-B glycoprotein levels were decreased, compared to normals.
7	9548303	Compared to piroxicam, tenidap lowered levels of alpha1-antiprotease and SAA but raised the levels of transthyretin, Gc-globulin, alpha2-HS-glycoprotein and alpha2-macroglobulin in RA patients.
8	9548303	Typhoid vaccination increased levels of SAA, haptoglobin alpha1, haptoglobin alpha2, haptoglobin beta and alpha1-anti-chymotrypsin but decreased transthyretin and apolipoprotein E.
9	9548303	In RA patients, serum amyloid A (SAA), haptoglobin alpha2, haptoglobin beta, alpha1-antichymotrypsin and C3 proactivator levels were elevated while apolipoprotein A-I, apolipoprotein A-IV, transthyretin, Gc-globulin, alpha2-HS glycoprotein, alpha2-macroglobulin and alpha1-B glycoprotein levels were decreased, compared to normals.
10	9548303	Compared to piroxicam, tenidap lowered levels of alpha1-antiprotease and SAA but raised the levels of transthyretin, Gc-globulin, alpha2-HS-glycoprotein and alpha2-macroglobulin in RA patients.
11	14514149	Correlation between the severity of infectious diseases in children and the ratio of serum amyloid A protein and C-reactive protein.
12	14514149	The aim of this study was to assess whether measurements of serum amyloid A protein (SAA) could provide additional information on the severity of acute infection beyond that obtained from C-reactive protein (CRP) assays.
13	14514149	The SAA and CRP concentrations were analysed from the sera of 334 children hospitalized for suspected pneumonia, meningitis or sepsis.
14	14514149	SAA significantly correlated with CRP (r = 0.682, p < 0.001) and did not alone provide any further clinically useful information.
15	14514149	By contrast, the median ratio (and interquartile range) of SAA to CRP varied significantly between clinical conditions of different severity and was significantly lower in the patients who died [1.9 (0.0-8.9)] than in those who survived [6.8 (3.2-13.6)] (p = 0.001).
16	14514149	Correlation between the severity of infectious diseases in children and the ratio of serum amyloid A protein and C-reactive protein.
17	14514149	The aim of this study was to assess whether measurements of serum amyloid A protein (SAA) could provide additional information on the severity of acute infection beyond that obtained from C-reactive protein (CRP) assays.
18	14514149	The SAA and CRP concentrations were analysed from the sera of 334 children hospitalized for suspected pneumonia, meningitis or sepsis.
19	14514149	SAA significantly correlated with CRP (r = 0.682, p < 0.001) and did not alone provide any further clinically useful information.
20	14514149	By contrast, the median ratio (and interquartile range) of SAA to CRP varied significantly between clinical conditions of different severity and was significantly lower in the patients who died [1.9 (0.0-8.9)] than in those who survived [6.8 (3.2-13.6)] (p = 0.001).
21	14514149	Correlation between the severity of infectious diseases in children and the ratio of serum amyloid A protein and C-reactive protein.
22	14514149	The aim of this study was to assess whether measurements of serum amyloid A protein (SAA) could provide additional information on the severity of acute infection beyond that obtained from C-reactive protein (CRP) assays.
23	14514149	The SAA and CRP concentrations were analysed from the sera of 334 children hospitalized for suspected pneumonia, meningitis or sepsis.
24	14514149	SAA significantly correlated with CRP (r = 0.682, p < 0.001) and did not alone provide any further clinically useful information.
25	14514149	By contrast, the median ratio (and interquartile range) of SAA to CRP varied significantly between clinical conditions of different severity and was significantly lower in the patients who died [1.9 (0.0-8.9)] than in those who survived [6.8 (3.2-13.6)] (p = 0.001).
26	14514149	Correlation between the severity of infectious diseases in children and the ratio of serum amyloid A protein and C-reactive protein.
27	14514149	The aim of this study was to assess whether measurements of serum amyloid A protein (SAA) could provide additional information on the severity of acute infection beyond that obtained from C-reactive protein (CRP) assays.
28	14514149	The SAA and CRP concentrations were analysed from the sera of 334 children hospitalized for suspected pneumonia, meningitis or sepsis.
29	14514149	SAA significantly correlated with CRP (r = 0.682, p < 0.001) and did not alone provide any further clinically useful information.
30	14514149	By contrast, the median ratio (and interquartile range) of SAA to CRP varied significantly between clinical conditions of different severity and was significantly lower in the patients who died [1.9 (0.0-8.9)] than in those who survived [6.8 (3.2-13.6)] (p = 0.001).
31	15731045	Concentrations of serum amyloid A (SAA) increased significantly 3 h after both the primary (P <0.05) and booster (P <0.001) i.m. vaccinations, but not in i.n. vaccinated calves.
32	16187407	Local serum amyloid A (SAA) formation may be involved in deposition of AA-amyloid induced by conformational change of SAA resulting in amyloid formation, having tremendous food safety implications.
33	17335831	We compared changes in plasma C-reactive protein (CRP) and serum amyloid A (SAA) concentrations 48 h after a standardized inflammatory stimulus (adjuvanted influenza vaccination) in patients with quiescent CHD that had been manifested at onset as inducible myocardial ischemia (Group 1, n=26) or as acute coronary syndromes (ACS) (Group 2, n=34).
34	17335831	Changes in CRP and SAA, both absolute and percentage, were significantly correlated in Group 2 (r=0.60 and 0.66, both p<0.001).
35	17335831	We compared changes in plasma C-reactive protein (CRP) and serum amyloid A (SAA) concentrations 48 h after a standardized inflammatory stimulus (adjuvanted influenza vaccination) in patients with quiescent CHD that had been manifested at onset as inducible myocardial ischemia (Group 1, n=26) or as acute coronary syndromes (ACS) (Group 2, n=34).
36	17335831	Changes in CRP and SAA, both absolute and percentage, were significantly correlated in Group 2 (r=0.60 and 0.66, both p<0.001).
37	17867462	Serum amyloid A (SAA) is of interest as the circulating precursor of amyloid A protein, the fibrillar component of AA (secondary) amyloid deposits, and also as an extremely sensitive and rapid major acute phase protein.
38	17962945	In turn, the onset of the immunological eclipse was coincidental with the onset of a systemic inflammatory condition characterized by a high number of circulating and splenic polymorphonucleated neutrophils (PMN) displaying activation and Gr1(+)Mac1(+) phenotype and an increasing serum concentration of the pro-inflammatory cytokines TNF-alpha, IL-1beta and IL-6 cytokines and C-reactive protein (CRP) and serum A amyloid (SAA) phase acute proteins.
39	18814544	Genes encoding acute phase reactants in the liver were up-regulated with serum amyloid A (SAA) as the most pronounced with a 2299-fold increase at 24 h p.i.
40	21371917	Blood was sampled before and after vaccination to measure levels of serum amyloid A (SAA), fibrinogen, white blood cell counts (WBC) and iron.
41	23389932	Microarray analysis of whole-lung RNA revealed significant changes in the acute-phase protein serum amyloid A (SAA) levels between noninfected and infected mice, and these changes were attenuated by immunization.
42	23784011	Higher serum amyloid A (SAA) and C-reactive protein (CRP) levels in pre-vaccination plasma were unfavorable factors for overall survival (OS).
43	25635238	This review also discusses the role of several autotransporter proteins (EhaA-D, EspP, Saa and Sab, and Cah), as well as other proteins associated with adherence, such as flagella, EibG, Iha, and OmpA.
44	25989623	Molecular characterization of two immunity-related acute-phase proteins: Haptoglobin and serum amyloid A from black rockfish (Sebastes schlegeli).
45	25989623	Haptoglobin (Hp) and serum amyloid A (SAA) are two vital proteins involved in inflammatory reactions and are classified as acute-phase proteins.