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Gene Information
Gene symbol: SCYL1
Gene name: SCY1-like 1 (S. cerevisiae)
HGNC ID: 14372
Synonyms: HT019, P105, GKLP, NKTL, TAPK, TRAP, TEIF, MGC78454
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CBL | 1 hits |
| 2 | CCDC91 | 1 hits |
| 3 | CD4 | 1 hits |
| 4 | CD40 | 1 hits |
| 5 | GORASP1 | 1 hits |
| 6 | LCK | 1 hits |
| 7 | NFATC2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21177920 | Here, we investigated the protein levels of nuclear transcription factor NF-κB (p50, p65, and p105), IκBα (inhibitor of NF-κB), T-cell receptor (TCR) CD3ζ-chain, tyrosine kinase p56(LCK), and nuclear factor of activated T cells c2 (NF-ATc2) in peripheral blood CD4(+) T cells from patients with sarcoidosis. |
| 2 | 21177920 | The reduced levels of p65 in sarcoid CD4(+) T cells concurred with decreased levels of p50, p105, CD3ζ, p56(LCK), IκBα, and NF-ATc2. |
| 3 | 21177920 | Polyclonal stimulation of NF-κB-deficient sarcoid T cells resulted in reduced expression of CD69 and CD154, decreased proliferation, and cytokine (i.e., interleukin 2 [IL-2] and gamma interferon [IFN-γ]) production. |
| 4 | 21177920 | Here, we investigated the protein levels of nuclear transcription factor NF-κB (p50, p65, and p105), IκBα (inhibitor of NF-κB), T-cell receptor (TCR) CD3ζ-chain, tyrosine kinase p56(LCK), and nuclear factor of activated T cells c2 (NF-ATc2) in peripheral blood CD4(+) T cells from patients with sarcoidosis. |
| 5 | 21177920 | The reduced levels of p65 in sarcoid CD4(+) T cells concurred with decreased levels of p50, p105, CD3ζ, p56(LCK), IκBα, and NF-ATc2. |
| 6 | 21177920 | Polyclonal stimulation of NF-κB-deficient sarcoid T cells resulted in reduced expression of CD69 and CD154, decreased proliferation, and cytokine (i.e., interleukin 2 [IL-2] and gamma interferon [IFN-γ]) production. |
| 7 | 21799517 | In c-Cbl-deficient dendritic cells, Toll-like receptor-induced expression of proinflammatory factors, such as interleukin-12, is increased, correlating with a greater potency of dendritic-cell-based vaccines against established tumours. |
| 8 | 21799517 | In addition, c-Cbl deficiency reduces both p50 and p105 levels, which have been shown to modulate the stimulatory function of NF-κB. |