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Gene Information
Gene symbol: SELP
Gene name: selectin P (granule membrane protein 140kDa, antigen CD62)
HGNC ID: 10721
Synonyms: CD62, PSEL, PADGEM, GMP140, CD62P
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCR7 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | IFNG | 1 hits |
| 4 | IL2 | 1 hits |
| 5 | IL2RA | 1 hits |
| 6 | IL8 | 1 hits |
| 7 | IL8RA | 1 hits |
| 8 | TXNRD1 | 1 hits |
| 9 | TXNRD2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15728501 | In this study we show that in HIV-infected individuals the loss of IL-7R (CD127) expression defines the expansion of a subset of CD8(+) T cells, specific for HIV as well as other Ags, that show phenotypic (i.e., loss of CCR7 and CD62 ligand expression with enrichment in activated and/or proliferating cells) as well as functional (i.e., production of IFN-gamma, but not IL-2, decreased ex vivo proliferative potential and increased susceptibility to apoptosis) features of effector T cells. |
| 2 | 15728501 | Importantly, in HIV-infected individuals the levels of CD8(+)CD127(-) T cells are directly correlated with the main markers of disease progression (i.e., plasma viremia and CD4(+) T cell depletion) as well as with the indices of overall T cell activation. |
| 3 | 15728501 | In all, these results identify the expansion of CD8(+)CD127(-) effector-like T cells as a novel feature of the HIV-associated immune perturbation. |
| 4 | 16275895 | Bovine natural killer (NK) cells were recently identified by positive selection of a NK cell-activating receptor p46 (NKp46)+ CD3- lymphocyte population, which expresses CD25 and CD8 and lyses tumor cell lines following stimulation with recombinant interleukin-2. |
| 5 | 16275895 | In the current work, we characterize the cytotoxic/effector potential of a CD3(-)CD8(-)CD11b- population isolated through negative selection of bovine peripheral blood leukocytes. |
| 6 | 16275895 | This population is CD25(lo)CD62(hi) when isolated and becomes CD25hiCD62L(lo) following cytokine stimulation. |
| 7 | 16275895 | Activated bovine NK cells increase expression of granulysin, interferon-gamma, and perforin and have cytotoxic activity against human tumor cells and Mycobacterium bovis bacillus Calmette-Guerin-infected alveolar and monocyte-derived macrophages. |
| 8 | 16275895 | Expression of a bovine homologue of the CD56 neural adhesion molecule expressed by human NK cells was detected in mRNA from brain tissue but was not detected in peripheral blood mononuclear cells or purified NK cell mRNA. |
| 9 | 16275895 | Analysis of mRNA from nonstimulated peripheral blood NK cells demonstrates the constitutive expression of homologues of human NK receptors NKp46, CD244, and CD94 and the granule proteins granulysin and perforin. |
| 10 | 16275895 | Phorbol ester-stimulated CD8+ T cells also expressed CD244 and CD94, and CD4+ T cells expressed CD94. |
| 11 | 24142411 | Calves fed the highest versus the lowest level of Se-enriched alfalfa hay had higher antibody titers (P = 0.02), thioredoxin reductase-2 mRNA levels (P = 0.07), and a greater neutrophil total antioxidant potential (P = 0.10), whereas mRNA levels of interleukin-8 receptor (P = 0.02), L-selectin (P = 0.07), and thioredoxin reductase-1 (P = 0.07) were lower. |