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Gene Information

Gene symbol: SERPINA3

Gene name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

HGNC ID: 16

Synonyms: ACT, alpha-1-antichymotrypsin

Related Genes

# Gene Symbol Number of hits
1 APLP2 1 hits
2 APOA1 1 hits
3 APOA4 1 hits
4 CFB 1 hits
5 CTSD 1 hits
6 GPHA2 1 hits
7 HP 1 hits
8 KLK3 1 hits
9 LPAL2 1 hits
10 RAG1 1 hits
11 SAA 1 hits
12 TTR 1 hits

Related Sentences

# PMID Sentence
1 8834614 Aim of the present study was to evaluate cathepsin D, base protease, antiplasmin, antitrypsin and antichymotrypsin activities and protein content in the 24h culture medium of the alveolar macrophages (AM) deriving from the rats treated BCG-vaccine and from rats with papain-induced emphysema.
2 9548303 Typhoid vaccination increased levels of SAA, haptoglobin alpha1, haptoglobin alpha2, haptoglobin beta and alpha1-anti-chymotrypsin but decreased transthyretin and apolipoprotein E.
3 9548303 In RA patients, serum amyloid A (SAA), haptoglobin alpha2, haptoglobin beta, alpha1-antichymotrypsin and C3 proactivator levels were elevated while apolipoprotein A-I, apolipoprotein A-IV, transthyretin, Gc-globulin, alpha2-HS glycoprotein, alpha2-macroglobulin and alpha1-B glycoprotein levels were decreased, compared to normals.
4 9548303 Compared to piroxicam, tenidap lowered levels of alpha1-antiprotease and SAA but raised the levels of transthyretin, Gc-globulin, alpha2-HS-glycoprotein and alpha2-macroglobulin in RA patients.
5 9620215 Various PSA-related concepts, including the ratio of "free" PSA and complexes of PSA with the protease inhibitor, alpha1-antichymotrypsin, to total PSA, have been proposed and placed within diagnostic and management algorithms.
6 23994886 In M3-9-M-bearing immunodeficient (Rag1) mice, ACT combined with ARI-4175 produced greater tumor responses and significantly improved survival compared with either treatment alone.