Ignet
Search (e.g., vaccine, IFNG): Help
About
Home
Introduction
Statistics
Programs
Dignet
Gene
GenePair
BioSummarAI
Help & Docs
Documents
Help
FAQs
Links
Acknowledge
Disclaimer
Contact Us
UM Logo

UMMS Logo

UMMS Logo

Gene Information

Gene symbol: SERPINB6

Gene name: serpin peptidase inhibitor, clade B (ovalbumin), member 6

HGNC ID: 8950

Synonyms: PTI, CAP

Related Genes

# Gene Symbol Number of hits
1 GZMB 1 hits
2 PTCRA 1 hits
3 SERPINB9 1 hits

Related Sentences

# PMID Sentence
1 3139417 409 cases of superficial bladder carcinoma (pTa, pTi, Tis) are reported.
2 14729651 Serine protease inhibitor 6 (SPI-6), also called Serpinb9, inhibits granzyme B and thus may provide a method for delaying apoptotic cell death in dendritic cells.
3 14729651 We have previously enhanced DNA vaccine potency by targeting antigen to MHC antigen presentation pathways, using proteins such as Mycobacterium tuberculosis heat shock protein 70, calreticulin, domain II of Pseudomonas aeruginosa exotoxin A, or the sorting signal of the lysosome-associated membrane protein type 1.
4 14729651 This combination of strategies resulted in significantly increased E7-specific CD8+ T-cell and CD4+ Th1-cell responses, enhanced tumor treatment ability, and stronger tumor protection when compared with vaccination without SPI-6.