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Gene Information

Gene symbol: SFTPA1

Gene name: surfactant protein A1

HGNC ID: 10798

Synonyms: SP-A, SP-A1, COLEC4

Related Genes

# Gene Symbol Number of hits
1 ADIPOQ 1 hits
2 CCR5 1 hits
3 HOXD13 1 hits
4 IFNG 1 hits
5 IL10 1 hits
6 IL6 1 hits
7 LTF 1 hits
8 MBL2 1 hits
9 MYO18A 1 hits
10 NOS2A 1 hits
11 SFTPD 1 hits
12 TGFB1 1 hits
13 TLR4 1 hits
14 TNF 1 hits
15 VDR 1 hits

Related Sentences

# PMID Sentence
1 10926544 Surfactant-associated protein A (SP-A) is involved in surfactant homeostasis and host defense in the lung.
2 10926544 TNF-alpha and nitric oxide production induced by BCG were enhanced by SP-A.
3 10926544 In addition, SP-A enhanced the BCG-induced increase in the level of inducible nitric oxide synthase protein.
4 10926544 Addition of antibodies directed against SPR210, a specific macrophage SP-A receptor, inhibited the SP-A-enhanced mediator production.
5 10926544 Surfactant-associated protein A (SP-A) is involved in surfactant homeostasis and host defense in the lung.
6 10926544 TNF-alpha and nitric oxide production induced by BCG were enhanced by SP-A.
7 10926544 In addition, SP-A enhanced the BCG-induced increase in the level of inducible nitric oxide synthase protein.
8 10926544 Addition of antibodies directed against SPR210, a specific macrophage SP-A receptor, inhibited the SP-A-enhanced mediator production.
9 10926544 Surfactant-associated protein A (SP-A) is involved in surfactant homeostasis and host defense in the lung.
10 10926544 TNF-alpha and nitric oxide production induced by BCG were enhanced by SP-A.
11 10926544 In addition, SP-A enhanced the BCG-induced increase in the level of inducible nitric oxide synthase protein.
12 10926544 Addition of antibodies directed against SPR210, a specific macrophage SP-A receptor, inhibited the SP-A-enhanced mediator production.
13 10926544 Surfactant-associated protein A (SP-A) is involved in surfactant homeostasis and host defense in the lung.
14 10926544 TNF-alpha and nitric oxide production induced by BCG were enhanced by SP-A.
15 10926544 In addition, SP-A enhanced the BCG-induced increase in the level of inducible nitric oxide synthase protein.
16 10926544 Addition of antibodies directed against SPR210, a specific macrophage SP-A receptor, inhibited the SP-A-enhanced mediator production.
17 11163458 The secreted antimicrobial molecules of the tubotympanum include lysozyme, lactoferrin, beta defensins, and the surfactant proteins A and D (SP-A, SP-D).
18 15588319 Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D.
19 18288962 However, in the absence of danger, such as during the clearance of apoptotic cells, defense collagens such as C1q, MBL, ficolins, SP-A, SP-D and even adiponectin have all been shown to facilitate enhanced phagocytosis and modulate induction of cytokines towards an anti-inflammatory profile.
20 24362687 Many studies have reported genetic associations between severe RSV bronchiolitis and SNPs in genes within plausible biological pathways, such as in innate host defense genes (SPA, SPD, TLR4, and VDR), cytokine or chemokine response genes (CCR5, IFN, IL6, IL10, TGFB1), and altered Th1/Th2 immune responses (IL4, IL13).