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Gene Information
Gene symbol: SH3GLB2
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CTLA4 | 1 hits |
| 2 | SPATA19 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18303116 | SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade. |
| 2 | 18303116 | Using a combination of active tumor vaccination in the presence of CTL-associated antigen 4 (CTLA-4) in vivo blockade, we elicited tumor-specific T cells used to expression clone the first T cell-defined TRAMP tumor antigen, called Spas-1 (stimulator of prostatic adenocarcinoma specific T cells-1). |
| 3 | 18303116 | Spas-1 expression was increased in advanced primary TRAMP tumors. |
| 4 | 18303116 | We show that the immunodominant SPAS-1 epitope SNC9-H(8) arose from a point mutation in one allele of the gene in TRAMP tumor cells, and that immunization with dendritic cells pulsed with SNC9-H(8) peptide resulted in protection against TRAMP-C2 tumor challenge. |
| 5 | 18303116 | In humans, the Spas-1 ortholog SH3GLB2 has been reported to be overexpressed in prostate cancer metastases. |
| 6 | 18303116 | SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade. |
| 7 | 18303116 | Using a combination of active tumor vaccination in the presence of CTL-associated antigen 4 (CTLA-4) in vivo blockade, we elicited tumor-specific T cells used to expression clone the first T cell-defined TRAMP tumor antigen, called Spas-1 (stimulator of prostatic adenocarcinoma specific T cells-1). |
| 8 | 18303116 | Spas-1 expression was increased in advanced primary TRAMP tumors. |
| 9 | 18303116 | We show that the immunodominant SPAS-1 epitope SNC9-H(8) arose from a point mutation in one allele of the gene in TRAMP tumor cells, and that immunization with dendritic cells pulsed with SNC9-H(8) peptide resulted in protection against TRAMP-C2 tumor challenge. |
| 10 | 18303116 | In humans, the Spas-1 ortholog SH3GLB2 has been reported to be overexpressed in prostate cancer metastases. |