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Gene Information
Gene symbol: SNRPD2
Gene name: small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
HGNC ID: 11159
Synonyms: Sm-D2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD14 | 1 hits |
| 2 | TLR4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22496731 | To study the mechanisms by which this occurs, we transfected HEK293T cells with plasmids encoding TLR4, CD14, and MD2 (three components of the LPS receptor complex), as well as a NFκB luciferase reporting system. |
| 2 | 22496731 | Both TLR4 and MD2 encoded by the plasmids are α-2,6 sialylated. |
| 3 | 22496731 | HEK293T cells transfected with TLR4/MD2/CD14 responded robustly to the addition of LPS; however, omission of the MD2 plasmid abrogated this response. |
| 4 | 22496731 | NA treatment of sMD2 enhanced the LPS response as did NA treatment of the TLR4/CD14-transfected cell supplemented with untreated sMD2, but optimal LPS-initiated responses were observed with NA-treated TLR4/CD14-transfected cells supplemented with NA-treated sMD2. |
| 5 | 22496731 | Overexpression of human Neu1 increased LPS-initiated TLR4-mediated NFκB activation and a NA inhibitor suppressed its activation. |