Ignet

Gene Information

Gene symbol: SPA17

Gene name: sperm autoantigenic protein 17

HGNC ID: 11210

Synonyms: SP17, CT22

Related Genes

#	Gene Symbol	Number of hits
1	ACRV1	1 hits
2	BIRC5	1 hits
3	BRD2	1 hits
4	CABYR	1 hits
5	CSAG1	1 hits
6	CTAG1B	1 hits
7	CTAGE1	1 hits
8	CTSG	1 hits
9	DDX43	1 hits
10	DDX53	1 hits
11	GNRH1	1 hits
12	HLA-A	1 hits
13	JARID1B	1 hits
14	MAGEC1	1 hits
15	PASD1	1 hits
16	PRAME	1 hits
17	SPAG9	1 hits
18	SPAM1	1 hits
19	TP53	1 hits
20	WT1	1 hits
21	ZP2	1 hits

Related Sentences

#	PMID	Sentence
1	11858857	Consequently we designed a ZP2-sperm antigen construct, replacing the C-terminal region of ZP2 with Sp17.
2	11872084	MAGE-C1 (CT7) gene expression in multiple myeloma: relationship to sperm protein 17.
3	12130509	In this study, we determined the ability to generate Sp17-specific HLA class I-restricted cytotoxic T lymphocytes (CTLs) from the peripheral blood of 4 patients with MM, 3 consecutive Sp17(+) patients, and 1 Sp17(-) patient.
4	14499726	Nowadays, the most acute researches are based on suppression of the secretion and the activity of gonadotropic hormones (GnRH, LH/hCG, FSH) or the targeting of antibodies specific to sperm surface (RSA-1, SP10, SP17, TCLe-1, PH-20) and oocyte antigens (ZP1, ZP2, ZP3).
5	18433090	This hypothesis is supported by the expression of two sperm fibrous sheath proteins, called sperm protein 17 and calcium-binding tyrosine-phosphorylation regulated protein, in tumors of unrelated histological origin and their capability to induce T cell-based immune responses.
6	20726502	The broadest mRNA expression profiles were observed for the following eight CT genes: Sp17 (25/25), PRAME (25/25), CSAGE (24/25), PASD1 (22/25), CAGE/DDX53 (19/25), CTAGE1 (19/25), HAGE/DDX43 (16/25) and PLU-1/JARID1B (15/25).
7	20885926	Expression of tumor antigens p53, SP17, survivin, WT1, and NY-ESO-1 was observed in 120 (48.0%), 173 (68.9%), 208 (90.0%), 129 (56.3%), and 27 (11.0%) of 270 tumor specimens, respectively.
8	24103781	Analysis of GAGE, NY-ESO-1 and SP17 cancer/testis antigen expression in early stage non-small cell lung carcinoma.
9	26263201	Sperm surface protein (Sp17) is a protein aberrantly expressed in primary as well as in metastatic lesions in >83% of ovarian cancer patients.
10	26263201	However, one of the 6 peptides, hSp17111-142, induced high levels of antibodies and IFN-γ producing T cells (but not IL-17 or IL-4) both in C57BL/6 and in C57BL/6-HLA-A2.1 transgenic mice.