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Gene Information
Gene symbol: SPINT1
Gene name: serine peptidase inhibitor, Kunitz type 1
HGNC ID: 11246
Synonyms: HAI, MANSC2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD19 | 1 hits |
| 2 | CD4 | 1 hits |
| 3 | FOXP3 | 1 hits |
| 4 | HAL | 1 hits |
| 5 | IFNG | 1 hits |
| 6 | IL4 | 1 hits |
| 7 | IL5 | 1 hits |
| 8 | ISG20 | 1 hits |
| 9 | NAAA | 1 hits |
| 10 | PRNT | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2163821 | Second stage resection was performed in 26 (16.8%) after marked reduction of the tumor by combination treatment with hepatic artery ligation (HAL) + hepatic artery infusion chemotherapy (HAI) + multifractionated radiotherapy (MFD) with linear accelerator, or radioimmunotherapy using 131I-anti human HCC ferritin antibody (131I-FtAb), which yielded the highest second stage resection rate (29.8%, 14/47) as compared to HAL + HAI or HAL + cryosurgery (16.9%, 12/71), HAL or HAI (0%, 0/37) alone. |
| 2 | 11456392 | Following two doses of primary vaccination, the seroconversion rate of PRNT and HAI antibody was 33.3% (10/30) [95% C.I. 17.3-52.5%] and 26.7% (8/30) [95% C.I. 12.3-45.9%], respectively. |
| 3 | 11456392 | The correlation between PRNT and HAI antibody showed a statistical significance (r=0.58, p<0.01). |
| 4 | 11456392 | Following two doses of primary vaccination, the seroconversion rate of PRNT and HAI antibody was 33.3% (10/30) [95% C.I. 17.3-52.5%] and 26.7% (8/30) [95% C.I. 12.3-45.9%], respectively. |
| 5 | 11456392 | The correlation between PRNT and HAI antibody showed a statistical significance (r=0.58, p<0.01). |
| 6 | 23370281 | In contrast, circulating CD4+CD25+% and CD4+FOXP3+% Treg increased after vaccination. |
| 7 | 23370281 | The decrease in IFNγ ELISPOT results was marginally associated with higher pH1N1-specific CD19+FOXP3+ and CD4+TGFβ+% Breg and Treg, respectively. |
| 8 | 23370281 | In contrast, increases in HAI titers post-dose 1 were associated with significantly higher circulating CD19+CD25+% post-dose 1, whereas increases in IFNγ ELISPOT results post-dose 1 were associated with higher circulating CD4+/C8+CD25+FOXP3+%. |
| 9 | 24361035 | Also, the level of the cytokines IL-6, TNF-α, IL-2, IFN-γ, IL-4 and IL-5 was quantified during the experimental study. |
| 10 | 24361035 | Moreover, early increases of TNF-alpha and IFN-gamma besides late increase of IFN-gamma were observed. |
| 11 | 24361035 | The analysis of biomarkers network pointed out two relevant strong axes during early stages of dengue fever, a protective axes TNF-alpha/Lymphocytes/Platelets, and a pathological IL-2/IL-6/Viremia/Monocyte/PT bond. |
| 12 | 24361035 | Later on, the biomarker network highlighted the interaction IFN-gamma/PLT/DENV-3(IgM;HAI)/PT, and the involvement of type-2 cytokines (IL-4; IL-5). |