Ignet
Search (e.g., vaccine, IFNG): Help
About
Home
Introduction
Statistics
Programs
Dignet
Gene
GenePair
BioSummarAI
Help & Docs
Documents
Help
FAQs
Links
Acknowledge
Disclaimer
Contact Us
UM Logo

UMMS Logo

UMMS Logo

Gene Information

Gene symbol: SPRY1

Gene name: sprouty homolog 1, antagonist of FGF signaling (Drosophila)

HGNC ID: 11269

Synonyms: hSPRY1

Related Genes

# Gene Symbol Number of hits
1 FOS 1 hits
2 LCK 1 hits
3 MAPK1 1 hits
4 MAPK10 1 hits

Related Sentences

# PMID Sentence
1 23166773 Previously, we had identified Egr-2 and Egr-3 as NF-AT-induced transcription factors which promote the inhibition of T cell activation.
2 23166773 Likewise, Spry1(Flox/Flox) Lck Cre CD8⁺ T cells display increased cytolytic activity.
3 23166773 Mechanistically, Spry1 acts at the level of PLC-γ promoting the inhibition of both Ca⁺⁺ induced NF-AT activation and MAP-kinase induced AP-1 activation while sparing NF-κB signaling.
4 23166773 Previously, we had identified Egr-2 and Egr-3 as NF-AT-induced transcription factors which promote the inhibition of T cell activation.
5 23166773 Likewise, Spry1(Flox/Flox) Lck Cre CD8⁺ T cells display increased cytolytic activity.
6 23166773 Mechanistically, Spry1 acts at the level of PLC-γ promoting the inhibition of both Ca⁺⁺ induced NF-AT activation and MAP-kinase induced AP-1 activation while sparing NF-κB signaling.