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Gene Information
Gene symbol: TFF2
Gene name: trefoil factor 2
HGNC ID: 11756
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | DMBT1 | 1 hits |
| 2 | KCNQ1 | 1 hits |
| 3 | MUC4 | 1 hits |
| 4 | PIGR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24866791 | In the later stages of infection, mRNA expression of H(+)/K(+)-ATPase α/β and KCNQ1 decreased, whereas the expression of Muc4, Tff2, Dmbt1, and polymeric immunoglobulin receptor (pIgR) increased starting at 16 weeks postinfection onwards, suggesting the existence of spasmolytic polypeptide-expressing metaplasia in the fundus of the stomach. |
| 2 | 24866791 | Our findings indicate that H. heilmannii infection causes severe gastric pathologies and alterations in the expression pattern of gastric mucins, such as Muc6 and Muc13, as well as disrupting gastric homeostasis by inducing the loss of parietal cells, resulting in the development of mucous metaplasia. |