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Gene Information

Gene symbol: THRB

Gene name: thyroid hormone receptor, beta

HGNC ID: 11799

Synonyms: THRB1, THRB2, NR1A2, THR1, ERBA-BETA, GRTH

Related Genes

#	Gene Symbol	Number of hits
1	DPEP1	1 hits
2	EGFR	1 hits
3	ERBB2	1 hits
4	IGF1R	1 hits

Related Sentences

#	PMID	Sentence
1	2509329	(ii) Interleukin-2 (IL-2), interferon-gamma (IFN-gamma) and N-acetyl muramyl-L-threonyl-D-isoglutamine ([Thr1]MDP), but not its liposoluble 6-O-stearoyl derivative (6-O-S-[Thr1]MDP), co-entrapped with the toxoid at appropriate phospholipid to toxoid ratios, generally reduced primary response to levels below those achieved with liposomes containing the antigen alone.
2	2509329	Further, responses obtained with 6-O-S[Thr1]MDP coentrapped with the toxoid or separately entrapped were higher than those seen with [Thr1]MDP in similar formulations.
3	2714847	The adjuvanticity of PC DRV was compared with that of aluminium salts (alum), complete Freund's adjuvant (CFA) and N-acetyl muramyl-L-threonyl-D-isoglutamine ([Thr1]MDP), the latter used as such or in a liposome form co-entrapped with the antigen.
4	2714847	DRV (with or without co-entrapped [Thr1]MDP), and alum were equally strong in producing primary and secondary immune responses (IgG1) to BSA.
5	2714847	Such responses were significantly higher than those achieved with CFA and [Thr1]MDP alone.
6	2714847	The adjuvanticity of PC DRV was compared with that of aluminium salts (alum), complete Freund's adjuvant (CFA) and N-acetyl muramyl-L-threonyl-D-isoglutamine ([Thr1]MDP), the latter used as such or in a liposome form co-entrapped with the antigen.
7	2714847	DRV (with or without co-entrapped [Thr1]MDP), and alum were equally strong in producing primary and secondary immune responses (IgG1) to BSA.
8	2714847	Such responses were significantly higher than those achieved with CFA and [Thr1]MDP alone.
9	2714847	The adjuvanticity of PC DRV was compared with that of aluminium salts (alum), complete Freund's adjuvant (CFA) and N-acetyl muramyl-L-threonyl-D-isoglutamine ([Thr1]MDP), the latter used as such or in a liposome form co-entrapped with the antigen.
10	2714847	DRV (with or without co-entrapped [Thr1]MDP), and alum were equally strong in producing primary and secondary immune responses (IgG1) to BSA.
11	2714847	Such responses were significantly higher than those achieved with CFA and [Thr1]MDP alone.
12	25941587	IGF-1R peptide vaccines/mimics inhibit the growth of BxPC3 and JIMT-1 cancer cells and exhibit synergistic antitumor effects with HER-1 and HER-2 peptides.
13	25941587	The insulin-like growth factor-1 receptor (IGF-1R) plays a crucial role in cellular growth, proliferation, transformation, and inhibition of apoptosis.
14	25941587	IGF-1R signaling interferes with numerous receptor pathways, rendering tumor cells resistant to chemotherapy, anti-hormonal therapy, and epidermal growth factor receptor (EGFR, also known as HER-1) and v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, (ERBB2, best known as HER-2) -targeted therapies.
15	25941587	In this study, we designed, synthesized, and characterized several B-cell epitopes from the IGF-1:IGF-1R axis.
16	25941587	Additionally, we found additive antitumor effects for the combination treatment of the IGF-1R 56-81 epitope with HER-1-418 and HER-2-597 epitopes.
17	25941587	Treatment with the IGF-1R/HER-1 or IGF-1R/HER-2 combination inhibited proliferation, invasion, and receptor phosphorylation, and induced apoptosis and ADCC, to a greater degree than single agents.