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Gene Information

Gene symbol: TIPARP

Gene name: TCDD-inducible poly(ADP-ribose) polymerase

HGNC ID: 23696

Synonyms: DKFZP434J214, DKFZp686N0351, DDF1, PARP7, PARP-7, PARP-1, pART14, RM1

Related Genes

# Gene Symbol Number of hits
1 CASP3 1 hits
2 PARP1 1 hits

Related Sentences

# PMID Sentence
1 24549367 Since chronic PARP-1 inhibition is also discussed to sacrifice neurogenesis and learning abilities, further experiments on neurons and in vivo studies could be helpful to clarify whether the inhibition of poly(ADP-ribosyl)ation contributes to organic Hg induced neurotoxicity.
2 25793397 Although the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway is one of the targets of NS1, the MFPTr virus suppressed the phosphorylation of Akt when compared with the wild-type (WT) virus.
3 25793397 It was suggested that this might lead to the subsequent inhibition of the cleavage of PARP-1 and caspase-3, which is important for the progression of apoptosis.
4 26084776 Detection of ADP ribosylation in PARP-1 and bacterial toxins using a capillary-based western system.