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Gene Information
Gene symbol: TJP1
Gene name: tight junction protein 1
HGNC ID: 11827
Synonyms: ZO-1, MGC133289, DKFZp686M05161
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD81 | 1 hits |
| 2 | CLDN1 | 1 hits |
| 3 | CLDN7 | 1 hits |
| 4 | OCLN | 1 hits |
| 5 | RHOD | 1 hits |
| 6 | TF | 1 hits |
| 7 | TFRC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18579606 | Combining confocal microscopy with biochemical analysis and studies of infection requirements using pharmacological inhibitors and small interfering RNAs, we show here that engagement of CD81 activates the Rho GTPase family members Rac, Rho, and Cdc42 and that the block of these signaling pathways drastically reduces HCV infectivity. |
| 2 | 18579606 | Activation of Rho GTPases mediates actin-dependent relocalization of the HCV E2/CD81 complex to cell-cell contact areas where CD81 comes into contact with the tight-junction proteins occludin, ZO-1, and claudin-1, which was recently described as an HCV coreceptor. |
| 3 | 25801707 | The influence of serogroup B strain MC58 on host cell polarity and intracellular trafficking system was assessed by confocal microscopy visualization of different plasma membrane-associated components (such as E-cadherin, ZO-1 and transferrin receptor) and evaluation of the transferrin uptake and recycling in infected Calu-3 monolayers. |
| 4 | 25801707 | Additionally, the association of N. meningitidis with different endosomal compartments was evaluated through the concomitant staining of bacteria and markers specific for Rab11, Rab22a, Rab25 and Rab3 followed by confocal microscopy imaging. |