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Gene Information
Gene symbol: TMEM171
Gene name: transmembrane protein 171
HGNC ID: 27031
Synonyms: PRP2
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
17875631
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A recombinant proline-rich antigen (rAg2/Pra) has been reported to be a leading vaccine candidate.
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2 |
17875631
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Subcutaneous vaccination of either C57BL/6 or BALB/c mice with rAg2/Pra plus adjuvant followed by intraperitoneal challenge with C. posadasii resulted in a significant reduction of the fungal burden at 12 to 14 days postchallenge compared to that in nonvaccinated animals.
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3 |
17875631
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Early studies of Ag2/Pra suggested that it is a component of an immunogenic complex.
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4 |
17875631
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We reveal in this study that C. posadasii produces a homolog of the reported proline-rich antigen, designated Prp2, which shows 69% protein sequence identity and 86% similarity to Ag2/Pra.
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5 |
17875631
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Protection against i.n. challenge of C57BL/6 mice was evaluated by vaccination with the single bacterially expressed homolog, rAg2/Pra, or rPrp2 in combination with rAg2/Pra, each in the presence of the same adjuvant.
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