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Gene Information
Gene symbol: TMEM173
Gene name:
HGNC ID:
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
21947006
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Cytosolic detection of pathogen-derived DNA is one major mechanism of inducing IFN production, and this process requires signalling through TANK binding kinase 1 (TBK1) and its downstream transcription factor, IFN-regulatory factor 3 (IRF3).
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2 |
21947006
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In addition, a transmembrane protein called STING (stimulator of IFN genes; also known as MITA, ERIS, MPYS and TMEM173) functions as an essential signalling adaptor, linking the cytosolic detection of DNA to the TBK1-IRF3 signalling axis.
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