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Gene Information

Gene symbol: TRADD

Gene name: TNFRSF1A-associated via death domain

HGNC ID: 12030

Synonyms: Hs.89862

Related Genes

# Gene Symbol Number of hits
1 CASP8 1 hits
2 CD40 1 hits
3 CD40LG 1 hits
4 FADD 1 hits
5 FAS 1 hits
6 IL4 1 hits

Related Sentences

# PMID Sentence
1 17378240 CD40L and IL-4 stimulation of acute lymphoblastic leukemia cells results in upregulation of mRNA level of FLICE--an important component of apoptosis.
2 17378240 Since it is still unclear whether CD40 ligation drives neoplastic B-cells to apoptosis or not, we assessed the mRNA expression of FLICE, FAS, FADD and TRADD - important components of apoptosis machinery, using real-time PCR in acute lymphoblastic leukemia cells before and after CD40 and IL-4 stimulation.
3 17378240 ALL cells stimulated with CD40L/IL-4 expressed dendritic cell phenotype at mRNA and protein levels (upregulation of main costimulatory and adhesion molecules noted in real-time RT PCR and flow cytometry); they also expressed higher amounts of mRNA for FLICE, TRADD and FADD after CD40L/IL-4 stimulation.
4 17378240 However differences statistically significant comparing cells cultured with CD40L/IL-4 and medium alone regarded only FLICE.
5 17378240 CD40L and IL-4 stimulation of acute lymphoblastic leukemia cells results in upregulation of mRNA level of FLICE--an important component of apoptosis.
6 17378240 Since it is still unclear whether CD40 ligation drives neoplastic B-cells to apoptosis or not, we assessed the mRNA expression of FLICE, FAS, FADD and TRADD - important components of apoptosis machinery, using real-time PCR in acute lymphoblastic leukemia cells before and after CD40 and IL-4 stimulation.
7 17378240 ALL cells stimulated with CD40L/IL-4 expressed dendritic cell phenotype at mRNA and protein levels (upregulation of main costimulatory and adhesion molecules noted in real-time RT PCR and flow cytometry); they also expressed higher amounts of mRNA for FLICE, TRADD and FADD after CD40L/IL-4 stimulation.
8 17378240 However differences statistically significant comparing cells cultured with CD40L/IL-4 and medium alone regarded only FLICE.