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Gene Information

Gene symbol: TSPAN7

Gene name: tetraspanin 7

HGNC ID: 11854

Synonyms: DXS1692E, TALLA-1, A15, CD231

Related Genes

# Gene Symbol Number of hits
1 C8orf4 1 hits
2 FAS 1 hits
3 HLA-A 1 hits
4 IGKV2-23 1 hits
5 IGKV2-26 1 hits
6 IGKV2-30 1 hits
7 IGKV2D-18 1 hits
8 PBLD 1 hits

Related Sentences

# PMID Sentence
1 15214037 A naked Sindbis RNA replicon vector (SINrep5) encoding the herpes simplex virus type 1 protein VP22 linked to E7 (SINrep5-VP22/E7) generated significant antitumor effects against TC-1 and TC-1 P3(A15), tumors with down-regulated MHC class I expression.
2 15634978 Phylogenetic analysis and pairwise comparison with prototype enterovirus strains distinguished two different species: 25 isolates belonged to human enterovirus B species, and 30 isolates were identified as coxsackievirus A13, A15, A17, A18, A20, A21, and A24, belonging to the human enterovirus species C.
3 15979942 An E7-expressing murine tumor model with a downregulated Fas expression--TC-1 P3(A15) tumors--was created.
4 15979942 A DNA vaccine encoding calreticulin linked to E7 (CRT/E7) was able to generate protective and therapeutic antitumor effects against TC-1 P3(A15) tumors.
5 15979942 In vitro Ab depletion and in vivo adoptive experiments showed that the antitumor effect of E7-specific CD8+ T lymphocytes against the TC-1 P3(A15) tumor cells was through the Fas-FasL-dependent CTL effector mechanism, and the TC-1 P3(A15) tumor cells needed higher numbers of antigen-specific CD8+ T lymphocytes for in vivo elimination.
6 15979942 Our results demonstrated that chimeric CRT/E7 DNA vaccine resulted in control of tumors with downregulated Fas expression, highlighting the importance of the Fas-FasL pathway in the potent antitumor effect of antigen-specific CD8+ cytotoxic T lymphocytes and the role of Fas as part of in vivo tumor evasion.
7 17555819 The two peptides identified with the greatest sequence homology with the OspA epitope were MAWD-BP(276-288), which had identity at eight of the nine core amino acid residues, and T-span7(58-70), which had identity at six residues.
8 17555819 MAWD-BP mRNA was expressed by synoviocytes, while T-span7 mRNA was not.
9 17555819 Among 11 patients, 9 had T cell reactivity with OspA(161-170), 6 had responses to MAWD-BP(276-288), and 3 had reactivity with T-span7(58-70), but reactivity with the self-peptides was lower than that induced by the spirochetal epitope.
10 17555819 The two peptides identified with the greatest sequence homology with the OspA epitope were MAWD-BP(276-288), which had identity at eight of the nine core amino acid residues, and T-span7(58-70), which had identity at six residues.
11 17555819 MAWD-BP mRNA was expressed by synoviocytes, while T-span7 mRNA was not.
12 17555819 Among 11 patients, 9 had T cell reactivity with OspA(161-170), 6 had responses to MAWD-BP(276-288), and 3 had reactivity with T-span7(58-70), but reactivity with the self-peptides was lower than that induced by the spirochetal epitope.
13 17555819 The two peptides identified with the greatest sequence homology with the OspA epitope were MAWD-BP(276-288), which had identity at eight of the nine core amino acid residues, and T-span7(58-70), which had identity at six residues.
14 17555819 MAWD-BP mRNA was expressed by synoviocytes, while T-span7 mRNA was not.
15 17555819 Among 11 patients, 9 had T cell reactivity with OspA(161-170), 6 had responses to MAWD-BP(276-288), and 3 had reactivity with T-span7(58-70), but reactivity with the self-peptides was lower than that induced by the spirochetal epitope.