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Gene Information
Gene symbol: UNG
Gene name: uracil-DNA glycosylase
HGNC ID: 12572
Synonyms: UDG, UNG1, UNG2, HIGM4
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL18 | 1 hits |
| 2 | IL1B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22973033 | Vaccines expressing codon-optimized HIV subtype C consensus Env and Gag antigens were generated from MVA vector backbones that (i) harbor simultaneous deletions of four viral immune-modulatory genes, encoding an interleukin-18 (IL-18) binding protein, an IL-1β receptor, a dominant negative Toll/IL-1 signaling adapter, and CC-chemokine binding protein (MVAΔ4-HIV); (ii) harbor a deletion of an additional (fifth) viral gene, encoding uracil-DNA glycosylase (MVAΔ5-HIV); or (iii) represent the parental MVA backbone as a control (MVA-HIV). |
| 2 | 22973033 | Both modified vectors elicited up to 6-fold-higher frequencies of HIV-specific CD8 and CD4 T cell responses and up to 25-fold-higher titers of Env (gp120)-specific binding (nonneutralizing) antibody responses that were relatively transient in nature. |