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Gene Information
Gene symbol: USP14
Gene name: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
HGNC ID: 12612
Synonyms: TGT
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCR7 | 1 hits |
| 2 | CD4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12890630 | The CC chemokine receptor (CCR) 7 ligands CCL21 and CCL19 were recently described as essential elements for establishing the microenvironment needed to initiate optimal immune responses in secondary lymphoid tissues. |
| 2 | 12890630 | In the present study we have kinetically investigated the primary responses of naive DO11.10 TCR-transgenic CD4+ T cells (OVA323-339 peptide specific) adoptively transferred into normal BALB/c mice given plasmid DNA encoding CCR7 ligands. |
| 3 | 12890630 | The primary responses of CD4+ Tg-T cells in CCR7 ligand DNA recipients occurred more promptly, reaching levels higher than those observed in vector controls. |
| 4 | 12890630 | In addition following mucosal challenge of herpes simplex virus-immune mice with virus, those that had received CCL21 or CCL19 during priming contained a higher frequency of responding CD4 T cells in lymph nodes and the site of infection. |
| 5 | 12890630 | Moreover, CCL21- and CCL19-treated mice showed less severe disease and better survival following challenge. |