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Gene Information
Gene symbol: WDR68
Gene name: WD repeat domain 68
HGNC ID: 30915
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
16014633
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To address the roles of NXF1-related factors, we studied the two mouse NXF1 homologues, mNXF2 and mNXF7.
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2 |
16014633
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In neuronal cells, mNXF2, but not mNXF7, exhibited mRNA export activity similar to that of Tip-associated protein/NXF1.
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3 |
16014633
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Yeast two-hybrid interaction, coimmunoprecipitation, and in vitro binding studies showed that NXF proteins bound to brain-specific microtubule-associated proteins (MAP) such as MAP1B and the WD repeat protein Unrip.
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4 |
16014633
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Both in vitro and in vivo, MAP1B also bound to NXF export cofactor U2AF as well as to Staufen1 and Unrip.
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5 |
16014633
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We propose a model in which MAP1B tethers the NXF-associated mRNA to microtubules and facilitates their translocation along dendrites while Unrip provides a scaffold for the assembly of these transport intermediates.
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