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Gene Information

Gene symbol: WDR68

Gene name: WD repeat domain 68

HGNC ID: 30915

Related Genes

# Gene Symbol Number of hits
1 MAP1B 1 hits
2 NPAS4 1 hits

Related Sentences

# PMID Sentence
1 16014633 To address the roles of NXF1-related factors, we studied the two mouse NXF1 homologues, mNXF2 and mNXF7.
2 16014633 In neuronal cells, mNXF2, but not mNXF7, exhibited mRNA export activity similar to that of Tip-associated protein/NXF1.
3 16014633 Yeast two-hybrid interaction, coimmunoprecipitation, and in vitro binding studies showed that NXF proteins bound to brain-specific microtubule-associated proteins (MAP) such as MAP1B and the WD repeat protein Unrip.
4 16014633 Both in vitro and in vivo, MAP1B also bound to NXF export cofactor U2AF as well as to Staufen1 and Unrip.
5 16014633 We propose a model in which MAP1B tethers the NXF-associated mRNA to microtubules and facilitates their translocation along dendrites while Unrip provides a scaffold for the assembly of these transport intermediates.