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Gene Information
Gene symbol: XBPP1
Gene name: X-box binding protein pseudogene 1
HGNC ID: 12802
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AICDA | 1 hits |
| 2 | IRF4 | 1 hits |
| 3 | MYOZ2 | 1 hits |
| 4 | PRDM1 | 1 hits |
| 5 | SDC1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19376580 | VLPs stimulated the proliferation of B220(+)IgM(+)CD43(-)CD5(-) B2 cells and their differentiation to plasma cells that preferentially produce IgG2a antibodies. |
| 2 | 19376580 | Up-regulation of Blimp-1, XBP-1, IRF4, and AID genes, which are responsible for class-switch recombination and somatic hypermutation, was observed in VLP-activated B2 cells. |
| 3 | 19376580 | Stimulation of naïve splenocytes with VLPs led to a high expression of IL-12, RANTES and MIP, the cytokine milieu that favors B cell differentiation into IgG2a secreting cells. |
| 4 | 22215754 | First, immune-based therapies are being developed (eg, elotuzumab monoclonal antibody [MoAb]; CD138DM immunotoxin; MM cell-dendritic cell vaccines; CD138, CS-1, and XBP-1 peptide vaccines; anti-17 MoAb; and other treatments to overcome causes of immune dysfunction). |
| 5 | 22215754 | Moreover, agents targeting bone biology (eg, zoledronic acid, anti-DKK-1 MoAb, anti-B-cell activating factor MoAb and bortezomib, Btk inhibitor) show promise not only in preserving bone integrity but also against MM. |