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Gene Information

Gene symbol: ZNF395

Gene name: zinc finger protein 395

HGNC ID: 18737

Synonyms: PRF-1, HDBP2, PBF, DKFZp434K1210

Related Genes

# Gene Symbol Number of hits
1 CCR5 1 hits
2 CD27 1 hits
3 CD8A 1 hits
4 CXCR3 1 hits
5 EOMES 1 hits
6 GZMB 1 hits
7 IFNG 1 hits
8 IL7R 1 hits
9 KLRD1 1 hits
10 PRF1 1 hits
11 TNFSF13B 1 hits

Related Sentences

# PMID Sentence
1 18784835 Although human B cells bound both human and murine BLyS, nuclear accumulation of NF-kappaB p52, an indication of the induction of a protective anti-apoptotic response, following stimulation with human BLyS was more robust than that induced with murine BLyS suggesting a fundamental disparity in BLyS receptor signaling.
2 18784835 Efficient engraftment of both human B and T lymphocytes in NOD rag1(-/-) Prf1(-/-) immunodeficient mice treated with recombinant human BLyS is observed after adoptive transfer of human PBL relative to PBS treated controls.
3 22735807 We have previously shown that vaccination with the natural tumor peptide Melan-A-induced T cells with superior effector functions as compared with vaccination with the analog peptide optimized for enhanced HLA-A*0201 binding.
4 22735807 Here we found that natural peptide vaccination induced tumor-reactive CD8 T cells with frequent coexpression of both memory/homing-associated genes (CD27, IL7R, EOMES, CXCR3, and CCR5) and effector-related genes (IFNG, KLRD1, PRF1, and GZMB), comparable with protective Epstein-Barr virus-specific and cytomegalovirus-specific T cells.