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Gene Information
Gene symbol: ADCY10
Gene name: adenylate cyclase 10 (soluble)
HGNC ID: 21285
Synonyms: SAC, Sacy, SACI, HCA2, RP1-313L4.2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | PLCB1 | 1 hits |
| 2 | PTH | 1 hits |
| 3 | PTHLH | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9121603 | The first receptor which has been cloned and well characterized is "PTH/PTHrP receptor-1". |
| 2 | 9121603 | It is activated not only by PTH, but also by PTH-related peptide (PTHrP), via a signal transduction system involving G-proteins, adenylate cyclase and phospholipase C. |
| 3 | 9121603 | One or several receptors are probably expressed in the keratinocyte and the glomerular podocyte which are not identical with PTH/ PTHrP receptor-1. |
| 4 | 9121603 | A third receptor, which has been cloned recently and called "PTH2 receptor", recognizes solely PTH. |
| 5 | 9121603 | There is also evidence for a fourth receptor, called "C-PTH receptor", recognizing C-terminal PTH fragments which are generally considered to be biologically inactive. |
| 6 | 9121603 | Down-regulation of PTH/PTHrP receptor-1 mRNA expression could explain the well-known resistance to the action of PTH in chronic renal failure. |
| 7 | 9121603 | A mutation of PTH/PTHrP receptor-1 causes Jansen-type metaphyseal chondrodysplasia. |
| 8 | 9121603 | However, no alteration of the PTH/PTHrP receptor-1 gene structure has been found in type 1b pseudohypoparathyroidism. |