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Gene Information
Gene symbol: ITGAM
Gene name: integrin, alpha M (complement component 3 receptor 3 subunit)
HGNC ID: 6149
Synonyms: MAC-1, CD11b
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD14 | 1 hits |
| 2 | CD68 | 1 hits |
| 3 | CR1 | 1 hits |
| 4 | IL1B | 1 hits |
| 5 | ITGAX | 1 hits |
| 6 | ITGB2 | 1 hits |
| 7 | PECAM1 | 1 hits |
| 8 | TDGF3 | 1 hits |
| 9 | TDGF4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7743666 | Participation of CR1 (CD35), CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in membranoproliferative glomerulonephritis type I. |
| 2 | 7743666 | The numbers of CR3 (CD11b/CD18)- and CR4 (CD11c/CD18)-positive cells per glomerular cross-section were counted. |
| 3 | 7743666 | At the 1st Bx, no significant difference was found in the number of CR3+ or CR4+ cells between the two groups. |
| 4 | 7743666 | At the 2nd Bx, the numbers of both the CR3+ and CR4+ cells were significantly decreased only in group A (P < 0.01). |
| 5 | 7743666 | The numbers of CR3+ and CR4+ cells were significantly higher in cases with moderate or marked C3c deposits than in those with no or mild C3c deposits. |
| 6 | 7743666 | This irreversible decrease or loss of CR1 may partly contribute to the continuous C3c deposition and intraglomerular infiltration of CR3+ and CR4+ cells. |
| 7 | 9263995 | Concomitantly, the expression of IL-1 receptor type I (IL-1 RI), IL-1 receptor type II (IL-1 RII) and of IL-1 receptor antagonist (IL-1 RA) was analyzed. |
| 8 | 9263995 | Antibodies against antigens expressed on podocytes (PP-44), endothelial cells (CD31) and monocytes/macrophages (CD11b, CD14, CD68) were applied to attribute the expression of IL-1/IL-1 related peptides to intrinsic glomerular and/or blood-derived infiltrating cells. |
| 9 | 9263995 | In MGN and MCD/FSGS, the expression of both IL-1 forms is particularly noted in early stages of the disease and is not only accompanied by a marked reactivity for IL-1 RI, but also for IL-1 RA. |
| 10 | 9263995 | In segmental sclerosing lesions in FSGS and in IgA-GN with marked glomerular proliferation and/or sclerosis, a reduced expression of the PP-44 antigen and a diminished ability of podocytes to produce IL-1/IL-1 related peptides are noted. |