Ignet

Gene Information

Gene symbol: NUDT6

Gene name: nudix (nucleoside diphosphate linked moiety X)-type motif 6

HGNC ID: 8053

Synonyms: gfg-1, gfg, FGF2AS, FGF-AS

Related Genes

#	Gene Symbol	Number of hits
1	DES	1 hits
2	FGF1	1 hits
3	FGF10	1 hits
4	FGF2	1 hits
5	FGF7	1 hits

Related Sentences

#	PMID	Sentence
1	8200474	Analysis of the fibroblast growth factor-2 (FGF-2 or bFGF) proteins during chicken embryonic pattern formation and organogenesis revealed that three isoforms (18.5, 20.0, and 21.5 kDa) were synthesized by alternative translation initiation from one coding region.
2	8766154	We have used avidin-biotin-enhanced indirect immunohistochemistry to localize FGF-1 and FGF-2 in the rat kidney.
3	8766154	Intracellular immunoreactivity for FGF-1 and FGF-2 is co-localized in visceral (podocytes) and parietal (Bowman's capsule) glomerular epithelial cells, S3 segments of proximal tubules, distal tubules and collecting ducts in the cortex, and thick ascending limbs and collecting ducts in the medulla.
4	8766154	We have used avidin-biotin-enhanced indirect immunohistochemistry to localize FGF-1 and FGF-2 in the rat kidney.
5	8766154	Intracellular immunoreactivity for FGF-1 and FGF-2 is co-localized in visceral (podocytes) and parietal (Bowman's capsule) glomerular epithelial cells, S3 segments of proximal tubules, distal tubules and collecting ducts in the cortex, and thick ascending limbs and collecting ducts in the medulla.
6	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
7	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
8	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
9	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
10	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
11	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
12	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
13	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
14	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
15	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
16	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
17	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
18	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
19	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
20	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
21	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
22	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
23	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
24	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
25	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
26	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
27	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
28	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
29	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
30	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
31	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
32	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
33	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
34	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
35	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
36	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
37	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
38	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
39	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
40	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
41	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
42	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
43	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
44	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
45	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
46	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
47	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
48	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
49	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
50	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
51	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
52	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
53	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
54	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
55	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
56	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
57	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
58	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
59	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
60	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
61	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
62	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
63	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
64	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
65	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
66	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
67	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
68	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
69	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
70	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
71	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
72	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
73	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
74	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
75	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
76	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
77	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
78	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
79	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
80	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
81	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
82	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
83	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
84	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
85	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
86	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
87	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
88	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
89	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
90	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
91	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
92	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
93	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
94	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
95	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
96	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
97	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
98	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
99	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
100	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
101	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
102	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
103	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
104	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
105	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.
106	11591823	To examine the potential role of fibroblast growth factor (FGF) signalling during cell differentiation, we used conditionally immortalised podocyte cells isolated from kidneys of Fgf2 mutant and wild-type mice.
107	11591823	Wild-type mouse podocyte cells upregulate FGF2 expression when differentiating in culture, as do maturing podocytes in vivo.
108	11591823	Molecular analysis of Fgf2 mutant mouse podocyte cells reveals a general disruption of FGF signalling as expression of Fgf7 and Fgf10 are also downregulated.
109	11591823	To examine the potential role of fibroblast growth factor (FGF) signalling during cell differentiation, we used conditionally immortalised podocyte cells isolated from kidneys of Fgf2 mutant and wild-type mice.
110	11591823	Wild-type mouse podocyte cells upregulate FGF2 expression when differentiating in culture, as do maturing podocytes in vivo.
111	11591823	Molecular analysis of Fgf2 mutant mouse podocyte cells reveals a general disruption of FGF signalling as expression of Fgf7 and Fgf10 are also downregulated.
112	11591823	To examine the potential role of fibroblast growth factor (FGF) signalling during cell differentiation, we used conditionally immortalised podocyte cells isolated from kidneys of Fgf2 mutant and wild-type mice.
113	11591823	Wild-type mouse podocyte cells upregulate FGF2 expression when differentiating in culture, as do maturing podocytes in vivo.
114	11591823	Molecular analysis of Fgf2 mutant mouse podocyte cells reveals a general disruption of FGF signalling as expression of Fgf7 and Fgf10 are also downregulated.