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Gene Information

Gene symbol: PODXL

Gene name: podocalyxin-like

HGNC ID: 9171

Synonyms: PCLP, Gp200, PC

Related Genes

# Gene Symbol Number of hits
1 CD34 1 hits
2 CHKA 1 hits
3 CR1 1 hits
4 PTPRO 1 hits
5 SYNPO 1 hits

Related Sentences

# PMID Sentence
1 8600307 Glomerular epithelial protein 1 and podocalyxin-like protein 1 in inflammatory glomerular disease (crescentic nephritis) in rabbit and man.
2 9625756 Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34.
3 9625756 Podocalyxin-like protein (PCLP) is a transmembrane sialomucin that is similar in structure to the well-characterized L-selectin ligand CD34.
4 9625756 These results suggest a novel function for PCLP as an adhesion molecule and allow the definition of conserved structural features in PCLP and CD34, which may be important for L-selectin ligand function.
5 9625756 Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34.
6 9625756 Podocalyxin-like protein (PCLP) is a transmembrane sialomucin that is similar in structure to the well-characterized L-selectin ligand CD34.
7 9625756 These results suggest a novel function for PCLP as an adhesion molecule and allow the definition of conserved structural features in PCLP and CD34, which may be important for L-selectin ligand function.
8 9625756 Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34.
9 9625756 Podocalyxin-like protein (PCLP) is a transmembrane sialomucin that is similar in structure to the well-characterized L-selectin ligand CD34.
10 9625756 These results suggest a novel function for PCLP as an adhesion molecule and allow the definition of conserved structural features in PCLP and CD34, which may be important for L-selectin ligand function.
11 9811343 To determine the relationship between cell cycle regulation and differentiation, the spatiotemporal expression of cyclin A, cyclin B1, cyclin D1, the cyclin-dependent kinase inhibitors (CKIs) p27 and p57, and markers of differentiating podocytes in developing human kidneys was investigated by immunohistochemistry.
12 9811343 In S-shaped body stage, Ki-67, a cell proliferation marker that labels the G1/S/G2/M phase, was expressed in the majority (more than 80%) of presumptive podocytes, along with cyclin A (approximately 20% of the Ki-67-positive cells) and cyclin B1 (less than 5% of Ki-67-positive cells) expression.
13 9811343 Among these cells), cyclin D1 and CKIs were markedly down-regulated.
14 9811343 At the capillary-loop stage, by contrast, CKIs and cyclin D1 were intensely positive in podocytes, whereas no Ki-67, cyclin B1, or cyclin A expression was seen.
15 9811343 Moreover, double-immunolabeling and serial-section analysis provided evidence that CKIs and markers specific for differentiating podocytes, namely PHM-5 (podocalyxin-like protein in humans), synaptopodin (a foot process-related protein), and C3b receptor, were co-expressed at the capillary-loop stage.
16 9811343 Furthermore, bcl-2 (an apoptosis inhibitory protein) showed a reciprocal expression pattern to that of CKI.