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Gene Information
Gene symbol: RPL10
Gene name: ribosomal protein L10
HGNC ID: 10298
Synonyms: NOV, QM, DXS648E, DXS648, FLJ23544, L10
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDKN1A | 1 hits |
| 2 | HGF | 1 hits |
| 3 | SIM1 | 1 hits |
| 4 | VEGFA | 1 hits |
| 5 | WT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9108440 | Induction of p21 by the Wilms' tumor suppressor gene WT1. |
| 2 | 9108440 | We have recently shown that inducible expression of WT1 in osteosarcoma cells triggers programmed cell death, an effect that is associated with transcriptional repression of the endogenous epidermal growth factor receptor. |
| 3 | 9108440 | We now show that WT1-mediated apoptosis is preceded by induction of the cyclin-dependent kinase inhibitor p21, associated with G1 phase arrest. |
| 4 | 9108440 | This effect is only demonstrated by WT1 isoforms with an intact DNA binding domain, and it is associated with increased expression of endogenous p21 mRNA. |
| 5 | 9108440 | WT1-mediated induction of p21 is independent of p53, another tumor suppressor gene known to regulate p21 expression. |
| 6 | 9108440 | In the kidney, p21 is expressed in differentiating glomerular podocytes along with WT1. |
| 7 | 9108440 | We conclude that induction of p21 expression may contribute to WT1-dependent differentiation pathways in the kidney and potentially to the function of WT1 as a tumor suppressor gene. |
| 8 | 9627060 | Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein. |
| 9 | 9627060 | We have produced and characterized three monoclonal antibodies (MAbs) directed to the amino terminus of the WT1 Wilms' tumor suppressor transcription factor and compared their properties to rabbit polyclonal sera raised to the same immunogen. |
| 10 | 9627060 | The WT1 antibodies do not recognize the structurally and functionally related early growth response (EGR)1, EGR2, EGR3, or EGR4 proteins. |
| 11 | 9627060 | Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein. |
| 12 | 9627060 | We have produced and characterized three monoclonal antibodies (MAbs) directed to the amino terminus of the WT1 Wilms' tumor suppressor transcription factor and compared their properties to rabbit polyclonal sera raised to the same immunogen. |
| 13 | 9627060 | The WT1 antibodies do not recognize the structurally and functionally related early growth response (EGR)1, EGR2, EGR3, or EGR4 proteins. |
| 14 | 10456263 | In addition, study of the Wilms' tumor suppressor, WT1, is revealing much about the pathogenesis of Wilms' tumor, urogenital development, and glomerular podocyte biology. c-met, the gene encoding the hepatocyte growth factor receptor, has recently been identified as a causative gene for hereditary papillary renal cancer. |
| 15 | 10769233 | In addition, pax2.1 expression in the lateral cells of the pronephric primordium is required to restrict the domains of Wilms' tumor suppressor (wt1) and vascular endothelial growth factor (VEGF) gene expression to medial podocyte progenitors. |
| 16 | 11493543 | We have defined regions of the intermediate mesoderm as candidates for the pronephric field by expression patterns of the Wilms' Tumor suppressor gene (wt1), single-minded 1 (sim1) and pax2.1. |