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Gene Information
Gene symbol: ACAT2
Gene name: acetyl-CoA acetyltransferase 2
HGNC ID: 94
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACAT1 | 1 hits |
| 2 | IGF2R | 1 hits |
| 3 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11032738 | In the whole-cell ACAT assay using CHO cells overexpressed with ACAT-1 or ACAT-2, GB inhibited the activity of both isozymes with similar potency. |
| 2 | 11283790 | These analyses implicated the same chromosomal region near marker D6S403 (6q22-q23) as harboring a major gene with strong pleiotropic effects on obesity and on lipid measures, including leptin concentrations (e.g., LOD(eq) for traits-specific insulin and leptin was 4.7). |
| 3 | 11283790 | A positional candidate gene for insulin resistance in this chromosomal region is the plasma cell-membrane glycoprotein PC-1 (6q22-q23). |
| 4 | 11283790 | The genetic location on chromosome 6q, near marker D6S264 (6q25.2-q26), was also identified by the bivariate analysis as exerting significant pleiotropic influences on IRS-related phenotypes (e.g., LOD(eq) for traits-specific insulin and leptin was 4.1). |
| 5 | 11283790 | This chromosomal region harbors positional candidate genes, such as the insulin-like growth factor 2 receptor (IGF2R, 6q26) and acetyl-CoA acetyltransferase 2 (ACAT2, 6q25.3-q26). |