Ignet

Gene symbol: AMFR

Gene name: autocrine motility factor receptor, E3 ubiquitin protein ligase

HGNC ID: 463

Synonyms: RNF45, gp78

Related Genes

Related Sentences

#	PMID	Sentence
1	17310145	We demonstrate by expressing recombinant proteins in Escherichia coli that Ube2g2/gp78-mediated polyubiquitination involves preassembly of Lys 48-linked ubiquitin chains at the catalytic cysteine of Ube2g2.
2	17310145	The growth of Ube2g2-anchored ubiquitin chains seems to be mediated by an aminolysis-based transfer reaction between two Ube2g2 molecules that each carries a ubiquitin moiety in its active site.
3	17310145	Intriguingly, polyubiquitination of a substrate can be achieved by transferring preassembled ubiquitin chains from Ube2g2 to a lysine residue in a substrate.