Ignet

Gene Information

Gene symbol: ANKRD1

Gene name: ankyrin repeat domain 1 (cardiac muscle)

HGNC ID: 15819

Synonyms: C-193, ALRP, CARP, CVARP, MCARP

Related Genes

#	Gene Symbol	Number of hits
1	ANKRD2	1 hits
2	ANKRD23	1 hits
3	CSRP3	1 hits
4	MARCKSL1	1 hits
5	MID1	1 hits
6	MID1IP1	1 hits
7	MSTN	1 hits
8	MT1A	1 hits
9	PDLIM5	1 hits
10	PSMD10	1 hits
11	RRAD	1 hits
12	SOCS3	1 hits
13	STAT3	1 hits
14	TTN	1 hits

Related Sentences

#	PMID	Sentence
1	17003243	Diabetes induced changes in mRNA expression of the proteins of titin stretch-sensing complexes in Z-disc (MLP, myostatin), I-band (CARP, Ankrd2), and M-line (titin kinase signaling).
2	17003243	In conclusion, we showed diabetes-induced changes in mRNA levels of several fiber-type-biased proteins (MLP, myostatin, Ankrd2) in skeletal muscle.
3	17392382	Previous studies identified the muscle ankyrin repeat protein (MARP) family, consisting of cardiac ankyrin repeat protein (CARP), ankyrin repeat domain 2/ankyrin repeat protein with PEST and proline-rich region (Ankrd2/Arpp), and diabetes-associated ankyrin repeat protein (DARP), as rapidly and specifically upregulated in mice after a single bout of EC.
4	17392382	This recovery was associated with enhanced expression of the muscle regulatory genes MyoD and muscle LIM protein (MLP), suggesting that the MARP family may play both important structural and gene regulatory roles in skeletal muscle.
5	18484352	Data from individual animals were used to identify genes in mouse skeletal muscle whose expression correlated with a known serum marker of skeletal myopathy, creatine kinase activity (CK), after treatment with a peroxisome proliferator-activated receptors (PPAR) agonist, GW610742X.
6	18484352	Six genes had correlation coefficients of >or=0.90: Mt1a (metallothionein 1a), Rrad (Ras-related associated with diabetes), Ankrd1 (ankyrin repeat domain 1), Stat3 (signal transducer and activator of transcription 3), Socs3 (suppressor of cytokine signalling 3) and Mid1ip1 (Mid1 interacting protein 1).
7	19150862	In this study, mRNA expression of titin, muscle LIM protein (MLP), cardiac ankyrin repeat protein (CARP), ankyrin repeat domain protein 2 (Ankrd2), diabetes-related ankyrin repeat protein (DARP), and calcium-activated proteinases, calpains, were investigated in human skeletal muscle after fatiguing jumping exercise.
8	19150862	Fatiguing jumping exercise did not change mRNA expression of titin, DARP, calpain 1, or calpain 3.
9	19150862	MLP, Ankrd2 and calpain 2 mRNA levels were increased 2 days postexercise.
10	19150862	Increased mRNA expression of MLP, CARP, and Ankrd2, observed for the first time in human skeletal muscle, may be part of the signaling activated by physical exercise.
11	19150862	In this study, mRNA expression of titin, muscle LIM protein (MLP), cardiac ankyrin repeat protein (CARP), ankyrin repeat domain protein 2 (Ankrd2), diabetes-related ankyrin repeat protein (DARP), and calcium-activated proteinases, calpains, were investigated in human skeletal muscle after fatiguing jumping exercise.
12	19150862	Fatiguing jumping exercise did not change mRNA expression of titin, DARP, calpain 1, or calpain 3.
13	19150862	MLP, Ankrd2 and calpain 2 mRNA levels were increased 2 days postexercise.
14	19150862	Increased mRNA expression of MLP, CARP, and Ankrd2, observed for the first time in human skeletal muscle, may be part of the signaling activated by physical exercise.
15	19967343	The three primary members, cardiac ankyrin repeat protein (CARP), Ankyrin Repeat Domain 2 (ARPP), and diabetes-related ankyrin repeat protein (DARP) are expressed in cardiac and skeletal muscle, binding to the giant protein titin.
16	19967343	In addition, both CARP and ARPP are proposed to have regulatory functions, shuttling to the nucleus and serving as a liaison between mechanical stress and the transcriptional response.
17	19967343	In mouse and human models, CARP is induced during wound healing, denervation, neurogenesis, and angiogenesis; ARPP during an immobilized stretch; DARP is up-regulated in type 2 diabetes, as well as brown adipose tissue, suggesting a role in energy metabolism.
18	19967343	The three primary members, cardiac ankyrin repeat protein (CARP), Ankyrin Repeat Domain 2 (ARPP), and diabetes-related ankyrin repeat protein (DARP) are expressed in cardiac and skeletal muscle, binding to the giant protein titin.
19	19967343	In addition, both CARP and ARPP are proposed to have regulatory functions, shuttling to the nucleus and serving as a liaison between mechanical stress and the transcriptional response.
20	19967343	In mouse and human models, CARP is induced during wound healing, denervation, neurogenesis, and angiogenesis; ARPP during an immobilized stretch; DARP is up-regulated in type 2 diabetes, as well as brown adipose tissue, suggesting a role in energy metabolism.
21	19967343	The three primary members, cardiac ankyrin repeat protein (CARP), Ankyrin Repeat Domain 2 (ARPP), and diabetes-related ankyrin repeat protein (DARP) are expressed in cardiac and skeletal muscle, binding to the giant protein titin.
22	19967343	In addition, both CARP and ARPP are proposed to have regulatory functions, shuttling to the nucleus and serving as a liaison between mechanical stress and the transcriptional response.
23	19967343	In mouse and human models, CARP is induced during wound healing, denervation, neurogenesis, and angiogenesis; ARPP during an immobilized stretch; DARP is up-regulated in type 2 diabetes, as well as brown adipose tissue, suggesting a role in energy metabolism.