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Gene Information

Gene symbol: APRT

Gene name: adenine phosphoribosyltransferase

HGNC ID: 626

Related Genes

#	Gene Symbol	Number of hits
1	GMPS	1 hits
2	HPRT1	1 hits
3	PFAS	1 hits
4	PPAT	1 hits

Related Sentences

#	PMID	Sentence
1	2451505	Measurements were made of the activity of phosphoribosyl pyrophosphate amidotransferase (PPRibP-At, EC 2.4.2.14) and of adenine (APRT, EC 2.4.2.7) and hypoxanthine (HPRT, EC 2.4.2.8) phosphoribosyltransferases, representing the 'de novo' and salvage pathways respectively.
2	2451505	PPRibP-At activity increased within 3 days of diabetes, whereas APRT and HPRT increased later.
3	2451505	Measurements were made of the activity of phosphoribosyl pyrophosphate amidotransferase (PPRibP-At, EC 2.4.2.14) and of adenine (APRT, EC 2.4.2.7) and hypoxanthine (HPRT, EC 2.4.2.8) phosphoribosyltransferases, representing the 'de novo' and salvage pathways respectively.
4	2451505	PPRibP-At activity increased within 3 days of diabetes, whereas APRT and HPRT increased later.
5	2451510	Measurements were made of the activities of the enzymes of the 'de novo' and salvage pathways of purine synthesis [phosphoribosyl pyrophosphate amidotransferase (EC 2.4.2.14), adenine phosphoribosyltransferase (EC 2.4.2.7) and hypoxanthine phosphoribosyltranferase (EC 2.4.2.8)] at different stages of the lactation cycle, and the effects of diabetes on the activity of these enzymes in lactation were studied.
6	3043317	Activities of de novo biosynthetic enzymes amidophosphoribosyltransferase, FGAM synthase, IMP dehydrogenase, GMP synthase, carbamoylphosphate synthase II were curtailed by 16-61%, those of salvage enzymes hypoxanthine-guanine-phosphoribosyltransferase, adenine-phosphoribosyltransferase, thymidine kinase also decreased to 31-58%.