|
Gene Information
Gene symbol: ARHGEF9
Gene name: Cdc42 guanine nucleotide exchange factor (GEF) 9
HGNC ID: 14561
Synonyms: KIAA0424, PEM-2
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
21626670
|
ARHGEF9 encodes collybistin (Cb) that plays an important role in the localization of gephyrin which is the key protein of the scaffolding system of inhibitory synapses and is essential for postsynaptic clustering of both GABA(A) and glycine receptors.
|
2 |
21626670
|
Cb-deficient male mice show reduced exploratory behavior, impaired spatial learning, increased anxiety scores, and reduction of gephyrin-dependent GABA receptor clusters in amygdala and hippocampus.
|
|